131066-80-3Relevant academic research and scientific papers
Quinazoline antifolates inhibiting thymidylate synthase: 4-thio-substituted analogues
Thornton,Jones,Jackman,Flinn,O'Connor,Warner,Calvert
, p. 978 - 984 (1991)
We report the synthesis of four new 4-thio-5,8-dideazafolic acid analogues and a 4-(methylthio) analogue structurally related to the thymidylate synthase (TS) inhibitor N10-propargyl-5,8-dideazafolic acid. Three N10-propargyl-4-thio-
