1310693-29-8Relevant academic research and scientific papers
3-SUBSTITUTED QUINOLINIUM AND 7H-INDOLO[2,3-c]QUINOLINIUM SALTS AS NEW ANTIINFECTIVES
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Page/Page column 7; 10, (2012/07/13)
The present invention relates to quinolinium antiinfective agents in which the qunolinium nucleus is fused to an indole ring or the qunolinium nucleus is linked to a cyclic structure through an opened indole or a benzothiophene or benzofuran ring. The compound is further substituted with various substituent groups. The compounds are represented by formula (I), (II) and (III): Pharmaceutical compositions and methods of use are also included.
δ-carbolines and their ring-opened analogs: Synthesis and evaluation against fungal and bacterial opportunistic pathogens
Mazu, Tryphon K.,Etukala, Jagan R.,Jacob, Melissa R.,Khan, Shabana I.,Walker, Larry A.,Ablordeppey, Seth Y.
, p. 2378 - 2385 (2011/06/22)
Previous studies have indicated that the δ-carboline (2) ring system derived from the natural product cryptolepine (1) may represent a pharmacophore for anti-infective activity. This paper describes the design and synthesis of a small library of substitut
