131071-73-3Relevant academic research and scientific papers
Design of a bioreductively-activated fluorescent pH probe for tumor hypoxia imaging
Nakata, Eiji,Yukimachi, Yoshihiro,Kariyazono, Hirokazu,Im, Seongwang,Abe, Chiaki,Uto, Yoshihiro,Maezawa, Hiroshi,Hashimoto, Toshihiro,Okamoto, Yasuko,Hori, Hitoshi
scheme or table, p. 6952 - 6958 (2010/01/16)
We have designed and evaluated UTX-12 as a novel fluorescent pH probe for tumor hypoxia imaging. UTX-12 consists of a p-nitro benzyl moiety, which is a latent hypoxia-selective leaving group activated by nitro reduction, directly linked to SNARF. Although
