1310875-94-5Relevant articles and documents
Discovery of a potent HIV integrase inhibitor that leads to a prodrug with significant anti-HIV activity
Seo, Byung I.,Uchil, Vinod R.,Okello, Maurice,Mishra, Sanjay,Ma, Xiao-Hui,Nishonov, Malik,Shu, Qingning,Chi, Guochen,Nair, Vasu
, p. 877 - 881 (2012/02/03)
Worldwide research efforts in drug discovery involving HIV integrase have produced only one compound, raltegravir, that has been approved for clinical use in HIV/AIDS. As resistance, toxicity, and drug-drug interactions are recurring issues with all class