131099-30-4Relevant academic research and scientific papers
Synthesis of amino 1,3-diols. Ring opening of N-acyl activated lactams with carbon nucleophiles
Klutchko,Hamby,Reily,Taylor,Hodges
, p. 971 - 983 (1993)
A synthesis of 6-amino-7-cyclohexyl-3,5-heptanediol 1 (CDH) and related amino 1,3-diols involving a nucleophilic ring opening of N-acyl activated lactams is described. Stereochemical proof of the 1,3-diol moiety is also presented.
