131111-13-2Relevant academic research and scientific papers
Copper-catalyzed Si-B bond activation in branched-selective allylic substitution of linear allylic chlorides
Vyas, Devendra J.,Oestreich, Martin
supporting information; experimental part, p. 8513 - 8515 (2011/01/05)
The harder they come, the better they leave! Chloride is superior to all common leaving groups in the γ-selective allylic substitution of linear precursors. This approach involves a novel copper-catalyzed Si-B bond activation (see scheme; γ/α≥98:2, 7-examples; Si=SiMe2Ph and B=Bpin with pin=pinacolato).
Expedient access to branched allylic silanes by copper-catalysed allylic substitution of linear allylic halides
Vyas, Devendra J.,Oestreich, Martin
supporting information; experimental part, p. 568 - 570 (2010/05/01)
An unprecedented copper-catalysed allylic transposition enables the regioselective synthesis of branched allylic silanes from linear allylic halides through direct C-Si bond formation.
