131114-06-2

Upstream product

• 369-32-4 1-(4-fluoro-3-methylphenyl)ethanone 
• 129083-90-5 methyl 2-(4-fluoro-3-methylphenyl)-4-oxo-6,6-dimethyl-cyclohex-2-enecarboxylate 
• 146299-76-5 methyl 4-fluoro-3-methylbenzoyl acetate 
• 141-79-7 4-methyl-pent-3-en-2-one 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 131114-05-1 Methyl 2-(4-fluoro-3-methylphenyl)-4-hydroxy-6, 6-dimethyl-cyclohex-2-en-1-carboxylate 

Downstream Products

• 129084-01-1 1-(4-Fluoro-3-methylphenyl)-3-(t-butyldimethylsilyloxy)-5,5-dimethyl-6-hydroxymethylcyclohexene 
• 129084-05-5 3-(2-(4-fluoro-3-methylphenyl)-4-(t-butyldimethylsilyl)oxy-6,6-dimethylcyclohex-1-en-1-yl)propenal 
• 131114-08-4 2-(4-fluoro-3-methylphenyl)-4-(t-butyldimethylsilyl)-oxy-6,6-dimethylcyclohex-1-enecarboxaldehyde 

Relevant academic research and scientific papers

Inhibitors of HMG-CoA reductase. Biological effects of A 6-[2-[2-(4-fluoro-3-methylphenyl)-4-substituted cyclohexe-1-en-1-yl]ethenyl]-4-hydroxy-3,4,5,6-tetrahydro-2h-pyran-2-o ne

We report on a series of potent inhibitors of HMG-CoA reductase (HMGR) that were designed to examine the biological consequences that result from molecular changes in RG 12561. The introduction of functional groups on the cyclohexene nucleus of RG 12561 a