129084-01-1Relevant academic research and scientific papers
Inhibitors of HMG-CoA reductase. Biological effects of A 6-[2-[2-(4-fluoro-3-methylphenyl)-4-substituted cyclohexe-1-en-1-yl]ethenyl]-4-hydroxy-3,4,5,6-tetrahydro-2h-pyran-2-o ne
Regan,Bruno,Gustafson,Amin,Neuenschwander,Perrone
, p. 735 - 742 (2007/10/02)
We report on a series of potent inhibitors of HMG-CoA reductase (HMGR) that were designed to examine the biological consequences that result from molecular changes in RG 12561. The introduction of functional groups on the cyclohexene nucleus of RG 12561 a
Substituted cyclohexene derivatives as HMG-CoA reductase inhibitors
-
, (2008/06/13)
Disclosed are novel 3-hydroxy-3-methylglutarylcoenzyme A reductase inhibitors useful as antihypercholesterolemic agents represented by the formula STR1 and the corresponding ring-opened hydroxy acids derived therefrom and pharmaceutically acceptable salts
Substituted cyclohexene derivatives as HMG-CoA reductase inhibitors
-
, (2008/06/13)
Disclosed are novel 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors useful as antihypercholesterolemic agents represented by the formula STR1 and the corresponding ring-opened hydroxy acids derived therefrom and pharmaceutically acceptable salt
Substituted cyclohexene derivatives as HMG-CoA reductase inhibitors
-
, (2008/06/13)
Disclosed are novel 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors useful as antihypercholesterolemic agents represented by the formula STR1 and the corresponding ring-opened hydroxy acids derived therefrom and pharmaceutically acceptable salt
