131124-01-1Relevant academic research and scientific papers
Perfluoralkylsubstituierte β-Chlorvinylaldehyde: Eine neue Klasse von building blocks zur Synthese fluorierter Heterocyclen
Greif, Dieter,Eilitz,Pulst,Riedel,Wecks
, p. 91 - 103 (2007/10/03)
By the preparation of β-chloro-β-perfluoroalkyl substituted acroleins, synthesized in three steps starting from benzylcyanide and ethyl perfluoroalkyl carboxylates, a versatile class of building blocks was obtained in good yields. β-Chloro-β-perfluoroalkyl substituted vinylaldehydes represent reactive C3-building blocks for preparing perfluoroalkyl substituted N-, S- and N,S-containing five and six membered heterocycles. A possible mechanism of formation of 5-CF3-substituted triazoles is discussed. Using p-xylylenedicyanide as starting material the reaction results in the formation of bis-β-chloro-β-perfluoroalkyl substituted acroleins. So it is possible to synthesize different bis-quinolins and also perfluoroalkyl substituted polymers with diazaanthracene or quinoline substructure.
Reactivity of a β-trifluoromethyl β-thioacrolein with various electrophiles
Alvernhe, Gerard M.,Greif, Dieter,Laurent, Andre J.,Pulst, Manfred,Weissenfels, Manfred
, p. 121 - 126 (2007/10/02)
Novel classes of trifluoromethylthiophenes and thiopyrans have been prepared by the reaction of a β-trifluoromethyl β-thioacrolein with different electrophiles, i.e. phenacyl bromide, enones or activated β-chlorovinylpropenes. - Keywords: β-Trifluoromethy
