1311275-90-7Relevant academic research and scientific papers
Synthesis of heterocycles through a ruthenium-catalyzed tandem ring-closing metathesis/isomerization/N-acyliminium cyclization sequence
Ascic, Erhad,Jensen, Jakob F.,Nielsen, Thomas E.
supporting information; experimental part, p. 5188 - 5191 (2011/06/26)
Tandem bicycle: In the title reaction double bonds created during ring-closing metathesis isomerize to generate reactive iminium intermediates that undergo intramolecular cyclization reactions with tethered heteroatom and carbon nucleophiles. In this way, a series of biologically interesting heterocyclic compounds can be made, including a known precursor for the total synthesis of the antiparasitic natural product harmicine. Copyright
