1311295-92-7Relevant academic research and scientific papers
Peptide/laccase cocatalyzed asymmetric α-oxyamination of aldehydes
Akagawa, Kengo,Kudo, Kazuaki
scheme or table, p. 3498 - 3501 (2011/09/14)
An asymmetric α-oxyamination could be successfully performed by a peptide catalyst and laccase. The combination of peptide catalysis and enzymatic air oxidation promoted the reaction smoothly in water without employing a metal reagent. The oxyaminated compounds could be obtained as both aldehyde and carboxylic acid products depending on the reaction conditions.
One-pot sequential alcohol oxidation and asymmetric α-oxyamination in aqueous media using recyclable resin-supported peptide catalyst
Akagawa, Kengo,Fujiwara, Takuma,Sakamoto, Seiji,Kudo, Kazuaki
supporting information; experimental part, p. 8040 - 8042 (2011/01/03)
An efficient tandem reaction system was developed, in which primary alcohols were used for the oxidation to the corresponding aldehydes followed by an asymmetric α-oxyamination with a resin-supported peptide catalyst.
