1311388-39-2

Upstream product

• 1311388-80-3 C₁₂H₆Cl₂O₃ 
• 1311388-61-0 C₂₂H₂₀ClNO₄ 
• 1333247-76-9 5-((4-chlorophenyl)(hydroxy)methyl)-N-(3,5-dimethoxyphenyl)-N-ethylfuran-2-carboxamide 
• 65650-09-1 5-(4-chloro-benzoyl)-furan-2-carboxylic acid 
• 65650-03-5 5-(4-chloro-benzoyl)-furan-2-carboxylic acid methyl ester 

Relevant academic research and scientific papers

A novel entry to spirofurooxindoles involving tandem dearomatization of furan ring and intramolecular friedel- Crafts reaction

A copper sulfate pentahydrate-catalyzed intramolecular Friedel-Crafts reaction using an oxocarbenium species derived from a furan ring as the alkylating agent was developed for the first time. By using this protocol, spirofurooxindoles 9 with multi-reactive sites were synthesized simply and concisely. In addition, selective hydrogenation of the endo-cyclic double bond and full hydrogenation of the endo and exo-cyclic double bonds of spirofurooxindoles 9 provided spirofurooxindoles 11 and 12, respectively. Copyright