131176-99-3

Upstream product

• 131110-72-0 2-p-Tolyl-4-trimethylsilanyl-cyclopentanone 
• 74-88-4 methyl iodide 
• 56917-71-6 5-trimethylsilyl-2-cyclohexanone 
• 131110-62-8 3-p-Tolyl-5-trimethylsilanyl-cyclohex-2-enone 
• 131110-66-2 6-p-Tolyl-4-trimethylsilanyl-7-oxa-bicyclo[4.1.0]heptan-2-one 
• 142944-74-9 (+)-3-p-tolyl-5-trimethylsilyl-3-(trimethylstannyl)cyclohexanone 
• 131110-72-0 (2S,4S)-2-p-Tolyl-4-trimethylsilanyl-cyclopentanone 
• 116215-94-2 (R)-(-)-5-trimethylsilyl-2-cyclohexenone 
• 142944-75-0 (S)-3-p-Tolyl-5-trimethylsilanyl-cyclohex-2-enone 
• 131110-66-2 (1S,4S,6R)-6-p-Tolyl-4-trimethylsilanyl-7-oxa-bicyclo[4.1.0]heptan-2-one 

Downstream Products

• 121402-69-5 (S)-(+)-5-methyl-5-(4-methylphenyl)cyclopent-2-en-1-one 

Relevant academic research and scientific papers

Lewis Acid-induced Reaction of Silicon-containing Stannyl Ketones and Its Application to the Synthesis of (+)-β-Cuparenone

Lewis acids activated only stannyl group in the silicon-containing stannyl ketones.The silyl group neither participated in the reaction directly, nor excerted any influences upon the reaction mode of the stannyl group.The reaction was applied for the synt

SYNTHESIS AND UTILIZATION OF OPTICALLY ACTIVE 2-SUBSTITUTED 4-(TRIMETHYLSILYL)CYCLOPENTANONES: SYNTHESIS OF (-)-MASSOIALACTONE AND (+)-β-CUPARENONE

Ring contraction by BF3*Et2O catalyzed epoxide rearrangement of 3-substituted 5-trimethylsilyl-2,3-epoxycyclohexanones gave the corresponding 2-substituted 4-(trimethylsilyl)cyclopentanones diastereoselectively.Synthesis of (-)-massoialactone and (+)-β-cuparenone utilizing the above transformation is also described.