142944-75-0

Upstream product

• 116215-94-2 (R)-(-)-5-trimethylsilyl-2-cyclohexenone 

Downstream Products

• 131110-66-2 (1S,4S,6R)-6-p-Tolyl-4-trimethylsilanyl-7-oxa-bicyclo[4.1.0]heptan-2-one 
• 131110-72-0 (2S,4S)-2-p-Tolyl-4-trimethylsilanyl-cyclopentanone 
• 131176-99-3 (2S,4S)-2-Methyl-2-p-tolyl-4-trimethylsilanyl-cyclopentanone 

Relevant academic research and scientific papers

SYNTHESIS AND UTILIZATION OF OPTICALLY ACTIVE 2-SUBSTITUTED 4-(TRIMETHYLSILYL)CYCLOPENTANONES: SYNTHESIS OF (-)-MASSOIALACTONE AND (+)-β-CUPARENONE

Ring contraction by BF3*Et2O catalyzed epoxide rearrangement of 3-substituted 5-trimethylsilyl-2,3-epoxycyclohexanones gave the corresponding 2-substituted 4-(trimethylsilyl)cyclopentanones diastereoselectively.Synthesis of (-)-massoialactone and (+)-β-cuparenone utilizing the above transformation is also described.