13118-70-2

Usage

Uses

Used in Pharmaceutical Industry:
Bicyclo(2.2.1)hept-2-en-7-ol, synis used as a reagent for the synthesis of potential modulators of CCR2 chemokine receptor activity. This application is significant because modulating the activity of CCR2 can have therapeutic effects on various diseases, including autoimmune disorders and certain types of cancer.
Used in Polymer Industry:
Bicyclo(2.2.1)hept-2-en-7-ol, synis also used as a useful reagent in polymerization reactions. Its unique structure and reactivity make it a valuable component in the development of new polymer materials with specific properties and applications.

InChI:InChI=1/C7H10O/c8-7-5-1-2-6(7)4-3-5/h1-2,5-8H,3-4H2

Upstream product

• 694-71-3 7-norbornenone 
• 278-74-0 exo-2,3-epoxynorbornane 
• 278-74-0 2,3-epoxynorbornane 
• 694-71-3 bicyclo<2.2.1>hept-2-en-7-one 
• 22365-94-2 anti-C₇H₉Br 
• 5371-40-4 toluene-4-sulfonic acid norborn-2-ene-7syn-yl ester 
• 31337-62-9 2-exo-bromonorbornan-7-syn-ol 
• 498-66-8 norborn-2-ene 
• 844874-18-6 exo-2,3-epoxynorbornane 

Downstream Products

• 36197-25-8 syn-7-Methoxy-bicyclo<2.2.1>hept-2-en 
• 361548-01-8 syn-7-(4-trifluoromethyl-phenoxy)-bicyclo[2.2.1]hept-2-ene 
• 361548-20-1 syn-7-(4-trifluoromethyl-benzyloxy)-bicyclo[2.2.1]hept-2-ene 
• 54560-85-9 syn-7-benzyloxy-bicyclo[2.2.1]hept-2-ene 
• 74808-92-7 exo-3,3-Fluorenylidenetricyclo<3.2.1.0^2,4>oct-anti-8-yl Tosylate 
• 746-47-4 tetrabenzo[5.5]fulvalene 
• 74808-91-6 exo-3,3-Fluorenylidenetricyclo<3.2.1.0^2,4>octan-anti-8-ol 
• 7176-92-3 syn-7-chloro-2-norbornanone 
• 36197-12-3 7-Norbornyl-methylaether 
• 361548-19-8 syn-7-(4-methoxy-benzyloxy)-bicyclo[2.2.1]hept-2-ene 

Relevant academic research and scientific papers

TETRAHYDROPYRANYL CYCLOPENTYL TETRAHYDROISOQUINOLINE MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY

The present invention is directed to compounds of the formula I: I(wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, X, n and the dashed line are defined herein) which are useful as modulators of chemokine receptor activity. In particular, these compounds are useful as modulators of the chemokine receptor CCR-2.

Catalytic asymmetric ring-opening metathesis/cross metathesis (AROM/CM) reactions. Mechanism and application to enantioselective synthesis of functionalized cyclopentanes

Studies regarding the first examples of catalytic asymmetric ring-opening metathesis (AROM) reactions are detailed. This enantioselective cleavage of norbornyl alkenes is followed by an intermolecular cross metathesis with a terminal olefin partner; judic

Modulation Of ?-Facial Selectivities In Nucleophilic Additions to 7-Norbornenones

The pronounced syn-face selectivity exhibited by 7-norbornenone in hydride reduction is dramatically altered (reversed) by the remote electron withdrawing substituents at the C2,C3-endo-position.Key Words: 7-Norbornenone, NaBH4 reduction, ?-face-selectivity.