278-74-0

Usage

Uses

Used in Organic Synthesis:
3-Oxatricyclo[3.2.1.02,4]octane is used as a building block in organic synthesis for its stable and strain-free structure, which is beneficial for creating various bioactive molecules and pharmaceuticals.
Used in Pharmaceutical Research:
In Pharmaceutical Research, 3-Oxatricyclo[3.2.1.02,4]octane is utilized as a key intermediate due to its potential in the development of new drugs, leveraging its interesting properties and reactivity.
Used in Drug Development:
3-Oxatricyclo[3.2.1.02,4]octane is employed in the development of new drugs, capitalizing on its unique structure and properties to enhance the discovery and synthesis of novel therapeutic agents.
Used in Material Science:
Although not explicitly mentioned in the provided materials, given its potential applications in the development of new materials due to its interesting properties and reactivity, 3-Oxatricyclo[3.2.1.02,4]octane could also be used in Material Science for creating innovative materials with specific properties.

InChI:InChI=1/C7H10O/c1-2-5-3-4(1)6-7(5)8-6/h4-7H,1-3H2

Upstream product

• 79-21-0 peracetic acid 
• 498-66-8 norborn-2-ene 
• 67-66-3 chloroform 
• 127-09-3 sodium acetate 
• 2311-91-3 monoperoxyphthalic acid 
• 60-29-7 diethyl ether 
• 98-83-9 isopropenylbenzene 
• 123073-89-2 Ru(IV)(octaethylporphyrin)(O)(EtOH) 
• 873-66-5 1-propenylbenzene 
• 498-66-8 norbornene 
• 62820-00-2 4-cyano-N,N-dimethylaniline-N-oxide 
• 542-92-7 cyclopenta-1,3-diene 
• 7732-18-5 water 
• 90466-73-2 3-exo-t-butylperoxytrinorbornan-2-yl 

Downstream Products

• 497-38-1 2-norbornanone 
• 497-36-9 (1R,4S)-Bicyclo[2.2.1]heptan-2-ol 
• 498-66-8 norborn-2-ene 
• 497-38-1 Norbornan-2-on 
• 14440-78-9 2,3-dihydroxybicyclo[2.2.1]hept-5-an 
• 872793-59-4 hexahydro-4,7-methanobenzo[d][1,3]dioxol-2-one 
• 24271-63-4 hexahydro-4,7-methanobenzo[d]oxazol-2(3H)-one 
• 497-36-9 (1S,2S,4R)-2-norbornanol 
• 694-70-2 syn-bicyclo<2.2.1>hept-2-en-7-ol 
• 13118-70-2 (1R,4S,7R)-Bicyclo[2.2.1]hept-2-en-7-ol 
• 1307304-86-4 C₁₈H₂₃NO₅ 
• 1307304-85-3 C₁₈H₂₁NO₅ 
• 625099-19-6 C₉H₁₄O₃ 
• 1491-12-9 2-norbornen-7-one ethylene acetal 

Relevant academic research and scientific papers

Fabrication of hierarchical composite microspheres of copper-doped Fe3O4@P4VP@ZIF-8 and their application in aerobic oxidation

Novel hierarchical magnetic composite microspheres of copper-doped Fe3O4@poly(4-vinylpyridine-co-divinylbenzene)@ZIF-8 (Cu-FPZ, Cu stands for copper doped) were successfully fabricated. The core-shell Fe3O4(PAA)@P4VP magnetic microspheres were first synthesized by a polymerization approach, in which the 4-vinylpyridine (4-VP) monomer interacted with a-COOH group of poly(acrylic acid) modified Fe3O4 by means of a hydrogen-bond interaction. Then Zn2+ was adsorbed on the surface of the P4VP shell, followed by the formation of a ZIF-8 porous shell with 2-methylimidazolate. Finally, nearly 5.45 wt% of copper content was incorporated with the ZIF-8 framework to form a magnetic core-shell copper-doped Fe3O4@P4VP@ZIF-8. The obtained copper-doped Fe3O4@P4VP@ZIF-8 catalyst was applied in the selective oxidation of alcohols and epoxidation of olefins using molecular oxygen as the oxidant. The results demonstrated that the magnetic core-shell copper-doped Fe3O4@P4VP@ZIF-8 catalyst showed better catalytic activity with significantly improved turnover number and turnover frequency (up to 8.25 h-1) than other copper MOFs. Furthermore, this heterogeneous catalyst could be cycled at least 15 times without significant loss of activity.

Binuclear molybdenum Schiff-base complex: An efficient catalyst for the epoxidation of alkenes

Dimolybdenum Schiff-base complex (DMSBC) which contain O,N-bidentate ligand was synthesized and characterized. The complex can be used as a promising catalyst in the epoxidation of olefins with tert-butyl-hydroperoxide (TBHP) as oxidant. The catalytic activity of the DMSBC was optimized by adjusting various parameters. Epoxidation of olefins by DMSBC indicated that the catalyst exhibited superb catalytic activity with high conversions up to 99.6%, high selectivity up to 100%, and high turnover frequency (TOF) of 208 h?1. Kinetic analysis provided that epoxidation of cyclooctene by DMSBC possessed moderate activation energy (95.3 ± 2 kJ·mol?1). Furthermore, the calculated pre-exponential factor (A) proved that strong collisions probability take place in the reaction. Additionally, the recycle experiments demonstrated that DMSBC could be recovered and repeatedly applied.

Catalytic hydrocarbon oxygenation by a dinuclear ruthenium(II) complex with molecular oxygen

A bis-μ-chloro Ru(II) dimer with tris(2-pyridylmethyl)amine (TPA) exhibited catalytic oxygenation of alkenes and cooxygenation of alkanes in the presence of cyclohexene with molecular oxygen (latm) at room temperature without reducing reagents; reactions proceeded via a radical chain mechanism as a main pathway.

Hydrogen-bond-supported 3D networks: Two different polymeric structures featuring chlorine atoms as ligands and as anions and investigations as epoxide catalysts

Two novel hydrogen-bonded network polymers, [MoO2Cl 2-(H2O)2]2[4,4′-H 2bipy]2+·2Cl- (1) and [MoO 2Cl4]2-[4,4′-H2-bipy] sup

A New Active Intermediate in Monooxygenations Catalyzed by Iron Porphyrin Complexes

A new type of high-valent oxoiron porphyrin (3b) has been prepared by the reaction of FeIII(tdcpp) (1b) [tdcpp: 5, 10,15,20-tetrakis(2,6-dichlorophenyl)porphyrin] with an oxidant such as p-nitroperbenzoic acid and pentafluoroiodosylbenzene at -

Epoxidation of Alkenes with Iodosylbenzene catalysed by a Water-soluble Chromium(III) N,N'-Ethylene bis(salicylideneaminato) (salen) Complex using β-Cyclodextrin as a Phase Transfer Agent

Addition of β-cyclodextrin as a phase-transfer agent resulted in an increase in yields and rates of epoxidation of alkenes with iodosylbenzene, catalysed by the water soluble complex Cl in water - methylene chloride.

Halogenated tetraphenyl porphyrin; Iodosylbenzene an efficient catalytic system for olefin epoxidation

Olefin epoxidation using o-phenyl and b-pyrrole substituted tetraphenyl porphyrin complexes of Fe(III) and Mn(III) as catalysts and yIodosylbenzene as oxidant was studied. Excellent yields of epoxide and secondary oxidation products were observed. Effect of pyridine, imadizole, sodium lauryl sulphate, and solvent variation was also studied. Effect of substituents on catalytic activity of the porphyrin complex is also explained. o-phenyl substituted complexes gave better yield of epoxide as compared to b-pyrrole substituted complexes.

Epoxidation of Alkenes Catalyzed by Iron(III) Schiff Base Chelates. A Monooxygenase Model

Iron(III) Schiff base chelates Cl2 (1), Cl2 (2), and Cl (3), were synthesized, where (PA2ppd), (PA2mpd), and (PA2opd) are the Schiff bases derived from 2-pyridinecarbaldehyde (PA), and p-phenylenediamine (p

Zirconium containing mesoporous silicas: New catalysts for oxidation reactions in the liquid phase

Zirconium containing mesoporous silicas are synthesized using hexadecylamine as surfactant; the new materials show very interesting properties as catalysts in liquid-phase oxidations with H2O2 and alkyl peroxides.

Effective alkene epoxidation with dilute hydrogen peroxide on amorphous silica-supported titanium catalysts

The use of amorphous silica-supported titanium catalysts in which the titanium ions display a chemical environment similar to that of Ti- substituted zeolites, afforded excellent activity in the epoxidation of terminal linear and bulky alkenes with dilute solutions of hydrogen peroxide.