131194-07-5Relevant academic research and scientific papers
A new class of HIV-1-specific 6-substituted acyclouridine derivatives: Synthesis and anti-HIV-1 activity of 5- or 6-substituted analogues of 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine (HEPT)
Tanaka,Baba,Hayakawa,Sakamaki,Miyasaka,Ubasawa,Takashima,Sekiya,Nitta,Shigeta,Walker,Balzarini,De Clercq
, p. 349 - 357 (2007/10/02)
A series of novel acyclouridine derivatives substituted at both the C-5 and C-6 positions were synthesized for the purpose of improving the activity of a recently reported HIV-1-specific lead, 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine (HEPT). Prep
