1312031-99-4Relevant academic research and scientific papers
Bulky, optically active P-stereogenic phosphine-boranes from pure H-menthylphosphinates
Gatineau, David,Giordano, Laurent,Buono, Gerard
, p. 10728 - 10731 (2011/09/14)
The transformation of readily available pure-H-menthylphosphinates into chiral phosphinous acid-boranes permits the elaboration of bulky P-stereogenic secondary phosphine-boranes. Taking advantage of the synthetic potential of these compounds, a broad range of hindered P-chiral tertiary phosphine-boranes has been prepared with excellent enantiomeric excesses. The utility of bulky o-tolylphosphines was illustrated by the synthesis of a rare enantiopure phosphapalladacycle (SP,SP)-12.
