1312208-30-2Relevant academic research and scientific papers
Effect of high pressure on the organocatalytic asymmetric michael reaction: Highly enantioselective synthesis of γ-nitroketones with quaternary stereogenic centers
Kwiatkowski, Piotr,Dudzinski, Krzysztof,Lyzzwa, Dawid
, p. 3624 - 3627 (2011)
The significant effect of hydrostatic pressure on the difficult organocatalytic 1,4-conjugate addition of nitroalkanes to prochiral sterically congested β,β-disubstituted enones is demonstrated. This approach allows for the synthesis of γ-nitroketones con
A general, highly enantioselective Michael addition of nitroalkanes to α,β-unsaturated enones catalyzed by 9-amino(9-deoxy)-epi-quinine: a remarkable additive effect
Liu, Siyang,Wang, Qingqing,Ye, Ling,Shi, Zhichuan,Zhao, Zhigang,Yang, Xuejun,Ding, Keyi,Li, Xuefeng
supporting information, p. 5115 - 5120 (2016/07/25)
A particularly general protocol for the organocatalytic asymmetric Michael addition of nitroalkanes to α,β-unsaturated enones is reported. The Michael reaction proceeded smoothly and provided the desired adducts in moderate to excellent yields (55–99%) an
