131230-71-2

Upstream product

• 68847-33-6 2-[(1,1,2,2-tetramethyl-1-silapropoxy)methyl]phenylamine 
• 96625-73-9 2,3-Dibromo-2-fluoropropanoyl bromide 

Downstream Products

• 131230-73-4 N-(2-hydroxymethyl phenyl)-3-bromo-3-fluoro-2-azetidinone 
• 131230-72-3 3-Bromo-1-[2-(tert-butyl-dimethyl-silanyloxymethyl)-phenyl]-3-fluoro-azetidin-2-one 

Relevant academic research and scientific papers

Inhibition of human leukocyte elastase by functionalized N-aryl-3,3-dihalogenoazetidin-2-ones. Stereospecific synthesis and chiral recognition of dissymmetrically C3-snbstituted β-lactams

(3R)- and (3S)-N-(2-chloromethylphenyl)-3-bromo-3-fluoroazetidin-2-ones 2 were synthesized via the separation of diastereoisomeric phenylglycinol derivatives of the starting 2,3-dibromo-2-fluoropropanoic acid. Acidic hydrolysis of the hydroxyamides led to