68847-33-6Relevant articles and documents
1H and 13C NMR spectral data of p-nitrobenzenesulfonamides and dansylsulfonamides derived from N-alkylated o-(Purinemethyl)anilines
Morales, Fátima,Campos, Joaquín M.,Conejo-García, Ana
, p. 760 - 770 (2016)
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Structure-activity relationships of natural quinone vegfrecine analogs with potent activity against VEGFR-1 and -2 tyrosine kinases
Adachi, Hayamitsu,Nosaka, Chisato,Atsumi, Sonoko,Nakae, Koichi,Umezawa, Yoji,Sawa, Ryuichi,Kubota, Yumiko,Nakane, Chie,Shibuya, Masabumi,Nishimura, Yoshio
, p. 734 - 742 (2021/07/25)
A series of analogs of vegfrecine, a natural quinone vascular endothelial growth factor receptor (VEGFR) tyrosine kinase inhibitor, was synthesized via oxidative amination of 2,5-dihydroxybenzamide with functionalized arylamine followed by ammonolysis and
Synthetic studies toward isoschizogamine: Construction of pentacyclic core structure
Sugimoto, Kenji,Fujiwara, Hiroaki,Takada, Akihiro,Kim, Dong-Gil,Ueda, Hirofumi,Tokuyama, Hidetoshi
, p. 1028 - 1049 (2019/07/31)
Development of a concise construction of the pentacyclic core skeleton of isoschizogamine was described. Tetracyclic A,B,D,F-rings structure was assembled by intramolecular aza-Diels–Alder reaction via an ortho-iminoquinone methide intermediate. The C-ring was formed by oxidation of the benzylic position with a combination of Cr(CO)6 and t-BuOOH, followed by the introduction of an aminoethyl side chain, C–H oxidation of the lactam ring with CrO3 and n-Bu4NI, and final cyclization to construct the cyclic aminal moiety.
