131230-79-0Relevant academic research and scientific papers
Inhibition of human leukocyte elastase by functionalized N-aryl azetidin-2-ones: Substituent effects at C-3 and benzylic positions
Vergely,Boggetto,Okochi,Golpayegani,Reboud-Ravaux,Kobaiter,Joyeau,Wakselman
, p. 199 - 208 (1995)
A series of functionalized N-aryl azetidin-2-ones with a latent alkylating group was prepared by a flexible four-step synthesis, They met criteria expected for a suicide-type inactivation of human leukocyte elastase (HLE) and porcine pancreatic elastase (
