1312302-18-3

Upstream product

• 153086-78-3 tert-butyl {2-[2-(2-aminoethoxy)ethoxy]ethyl}carbamate 
• 139115-92-7 tert-butyl 2-(2-(2-hydroxyethoxy)ethoxy)ethylcarbamate 
• 1312302-16-1 (2E,4E,6E,8E)-2-cyanoethyl 9-((E)-3-{2-[2-(2-{2-[(S)-2-((2S,3R)-3-{[(9H-fluoren-9-yl)methoxy]carbonylamino}-2-hydroxy-4-phenylbutanamido)-4-methylpentanamido]ethoxy}ethoxy)ethylamino]-2-oxoethoxyimino}-2,6,6-trimethylcyclohex-1-enyl)-3,7-dimethylnona-2,4,6,8-tetraenoate 
• 1312302-12-7 (S)-2-{2-[2-(tert-butoxycarbonylamino)ethoxy]ethoxy}ethyl 2-((2S,3R)-3-{[(9H-fluoren-9-yl)methoxy]carbonylamino}-2-hydroxy-4-phenyl-butanamido)-4-methylpentanamide 
• 206265-94-3 2,2-dimethyl-4-oxo-3,8,11-trioxa-5-azatridecane-13-yl 4-methylbenzenesulfonate 
• 950683-55-3 {2-[2-(2-azidoethoxy)ethoxy]ethyl}carbamic acid tert-butyl ester 

Downstream Products

• 1310451-45-6 (2E,4E,6E,8E)-9-[(E)-3-(2-{2-[2-(2-{(S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanamido]-4-methylpentanamido}ethoxy)ethoxy]ethylamino}-2-oxoethoxyimino)-2,6,6-trimethylcyclohex-1-enyl]-3,7-dimethylnona-2,4,6,8-tetraenoic acid 

Relevant academic research and scientific papers

Development of target protein-selective degradation inducer for protein knockdown

Our previous technique for inducing selective degradation of target proteins with ester-type SNIPER (Specific and Nongenetic Inhibitor-of-apoptosis- proteins (IAPs)-dependent Protein ERaser) degrades both the target proteins and IAPs. Here, we designed a