1312302-65-0Relevant academic research and scientific papers
Synthesis of novel chromene scaffolds for adenosine receptors
Costa, Marta,Areias, Filipe,Castro, Marian,Brea, Jose,Loza, Maria I.,Proena, Fernanda
experimental part, p. 4242 - 4249 (2011/07/29)
A one-pot procedure was developed for the synthesis of novel 3-[amino(methoxy)methylene]-2-oxo-3,4-dihydro-2H-chromen-4-yl) -3-cyanoacetamides and chromeno[3,4-c]pyridine-1-carbonitriles from the reaction of 2-oxo-2H-chromene-3-carbonitriles and cyanoacetamides. These chromene derivatives were identified as new scaffolds for adenosine receptors and the hits 3a, 3c, 5a, and 5b were found.
