1312341-49-3

Upstream product

• 123-73-9 trans-Crotonaldehyde 
• 1312341-52-8 (S)-4-benzyl-5,5-dimethyl-N-(3-methylbutanoyl)-1,3-oxazolidin-2-one 
• 168297-85-6 (S)-4-benzyl-5,5-dimethyloxazolidin-2-one 
• 108-12-3 isopentanoyl chloride 

Downstream Products

• 1312341-45-9 (S)-4-benzyl-3-((S)-2-((R)-hydroxy-((1S,2S)-2-methylcyclopropyl)methyl)-3-methylbutanoyl)-5,5-dimethyloxazolidin-2-one 

Relevant academic research and scientific papers

Asymmetric synthesis of chiral δ-lactones containing multiple contiguous stereocenters

A versatile methodology for the asymmetric synthesis of chiral δ-lactones containing multiple contiguous stereocenters has been developed that relies on a series of Evans' aldol, hydroxyl-directed cyclopropanation, methanolysis, and Hg(II) mediated cyclopropane ring-opening reactions for stereocontrol.