1312478-48-0

Basic information

• Product Name: (2R)-ethyl 4-bromo-2-methyl-2-(methylsulfonyl)butanoate
• Synonyms: (2R)-ethyl 4-bromo-2-methyl-2-(methylsulfonyl)butanoate
• CAS NO: 1312478-48-0
• Molecular Weight: 287.175
• Mol File: 1312478-48-0.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: (2R)-ethyl 4-bromo-2-methyl-2-(methylsulfonyl)butanoate(CAS DataBase Reference)
• NIST Chemistry Reference: (2R)-ethyl 4-bromo-2-methyl-2-(methylsulfonyl)butanoate(1312478-48-0)
• EPA Substance Registry System: (2R)-ethyl 4-bromo-2-methyl-2-(methylsulfonyl)butanoate(1312478-48-0)

Safety Data

• Hazardous Substances Data: 1312478-48-0(Hazardous Substances Data)

Usage

General Description

"(2R)-ethyl 4-bromo-2-methyl-2-(methylsulfonyl)butanoate" is a chemical compound with the molecular formula C8H15BrO4S. It is an ester, with a butanoate group attached to an ethyl group. The presence of a bromo and a methylsulfonyl group makes this compound reactive and potentially useful in organic synthesis and chemical processes. The stereochemistry of the molecule is specified as (2R), indicating that the chiral carbon in the molecule has a specific spatial orientation. (2R)-ethyl 4-bromo-2-methyl-2-(methylsulfonyl)butanoate may have potential applications in pharmaceutical, agrochemical, or material science industries, but further research and development would be required to determine its specific uses and properties.

Upstream product

• 535-13-7 2-chloro-propanoic acid, ethyl ester 
• 1312478-47-9 ethyl (±)-4-bromo-2-methyl-2-(methylsulfonyl)butanoate 
• 73017-82-0 Ethyl α-(methylsulfonyl)propionate 

Downstream Products

• 1312479-45-0 ethyl (2R)-4-(3-fluoro-2-oxo-4-phenylpyridin-1(2H)-yl)-2-methyl-2-(methylsulfonyl)butanoate 
• 1312479-46-1 (2R)-4-(3-fluoro-2-oxo-4-phenylpyridin-1(2H)-yl)-2-methyl-2-(methylsulfonyl)butanoic acid 
• 1312479-47-2 (2R)-4-(3-fluoro-2-oxo-4-phenylpyridin-1(2H)-yl)-2-methyl-2-(methylsulfonyl)-N-(tetrahydro-2H-pyran-2-yloxy)butanamide 
• 1312473-96-3 (2R)-4-(3-fluoro-2-oxo-4-phenylpyridin-1(2H)-yl)-N-hydroxy-2-methyl-2-(methylsulfonyl)butanamide 
• 1312479-49-4 ethyl (2R)-4-(5-fluoro-2-oxo-4-phenylpyridin-1(2H)-yl)-2-methyl-2-(methylsulfonyl)butanoate 
• 1402636-23-0 ethyl (2R)-2-methyl-4-(3-methyl-4-phenyl-1H-pyrazol-1-yl)-2-(methylsulfonyl)butanoate 
• 1402636-32-1 ethyl (2R)-2-methyl-2-(methylsulfonyl)-4-(4-phenyl-1H-pyrazol-1-yl)butanoate 
• 1402636-10-5 ethyl (2R)-4-[4-(cyclohex-1-en-1-yl)-1H-pyrazol-1-yl]-2-methyl-2-(methylsulfonyl)butanoate 
• 1402636-11-6 (2R)-4-[4-(cyclohex-1-en-1-yl)-1H-pyrazol-1-yl]-2-methyl-2-(methylsulfonyl)butanoic acid 
• 1402636-12-7 (2R)-4-[4-(cyclohex-1-en-1-yl)-1H-pyrazol-1-yl]-2-methyl-2-(methylsulfonyl)-N-(tetrahydro-2H-pyran-2-yloxy)butanamide 
• 1402636-09-2 (2R)-4-[4-(cyclohex-1-en-1-yl)-1H-pyrazol-1-yl]-N-hydroxy-2-methyl-2-(methylsulfonyl)butanamide 
• 1402636-64-9 ethyl (2R)-2-methyl-4-(4-methyl-5-phenyl-1H-1,2,3-triazol-1-yl)-2-(methylsulfonyl)butanoate 
• 1402636-13-8 (2R)-4-(4-cyclohexyl-1H-pyrazol-1-yl)-N-hydroxy-2-methyl-2-(methylsulfonyl)butanamide 
• 1402636-14-9 ethyl (2R)-4-(4-cyclohexyl-1H-pyrazol-1-yl)-2-methyl-2-(methylsulfonyl)butanoate 

Relevant articles and documents

FLUORO-PYRIDINONE PHOSPHATES AND BORONATES USEFUL AS ANTIBACTERIAL AGENTS

The present invention is directed to a new fluoro-pyridinone hydroxamic acid phosphates and boronates of Formulae (I), (II) and (III) wherein Q is selected from the group consisting of –P(O)(OH)2, –P(O)(OH)(O-M+), –P(O)(O-M+)2/

Pyridone methylsulfone hydroxamate LpxC inhibitors for the treatment of serious Gram-negative infections

The synthesis and biological activity of a new series of LpxC inhibitors represented by pyridone methylsulfone hydroxamate 2a is presented. Members of this series have improved solubility and free fraction when compared to compounds in the previously described biphenyl methylsulfone hydroxamate series, and they maintain superior Gram-negative antibacterial activity to comparator agents.

IMIDAZOLE, PYRAZOLE, AND TRIAZOLE DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS

The present invention is directed to a new class of hydroxamic acid derivatives, their use as Lpx C inhibitors and, more specifically, their use to treat bacterial infections.