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1312479-45-0

ethyl (2R)-4-(3-fluoro-2-oxo-4-phenylpyridin-1(2H)-yl)-2-methyl-2-(methylsulfonyl)butanoate is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 1312479-45-0 Structure

  • Basic information

    1. Product Name: ethyl (2R)-4-(3-fluoro-2-oxo-4-phenylpyridin-1(2H)-yl)-2-methyl-2-(methylsulfonyl)butanoate
    2. Synonyms: ethyl (2R)-4-(3-fluoro-2-oxo-4-phenylpyridin-1(2H)-yl)-2-methyl-2-(methylsulfonyl)butanoate
    3. CAS NO:1312479-45-0
    4. Molecular Formula:
    5. Molecular Weight: 395.452
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1312479-45-0.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: ethyl (2R)-4-(3-fluoro-2-oxo-4-phenylpyridin-1(2H)-yl)-2-methyl-2-(methylsulfonyl)butanoate(CAS DataBase Reference)
    10. NIST Chemistry Reference: ethyl (2R)-4-(3-fluoro-2-oxo-4-phenylpyridin-1(2H)-yl)-2-methyl-2-(methylsulfonyl)butanoate(1312479-45-0)
    11. EPA Substance Registry System: ethyl (2R)-4-(3-fluoro-2-oxo-4-phenylpyridin-1(2H)-yl)-2-methyl-2-(methylsulfonyl)butanoate(1312479-45-0)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1312479-45-0(Hazardous Substances Data)

1312479-45-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1312479-45-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,1,2,4,7 and 9 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1312479-45:
(9*1)+(8*3)+(7*1)+(6*2)+(5*4)+(4*7)+(3*9)+(2*4)+(1*5)=140
140 % 10 = 0
So 1312479-45-0 is a valid CAS Registry Number.

1312479-45-0Relevant articles and documents

Pyridone methylsulfone hydroxamate LpxC inhibitors for the treatment of serious Gram-negative infections

Montgomery, Justin I.,Brown, Matthew F.,Reilly, Usa,Price, Loren M.,Abramite, Joseph A.,Arcari, Joel,Barham, Rose,Che, Ye,Chen, Jinshan Michael,Chung, Seung Won,Collantes, Elizabeth M.,Desbonnet, Charlene,Doroski, Matthew,Doty, Jonathan,Engtrakul, Juntyma J.,Harris, Thomas M.,Huband, Michael,Knafels, John D.,Leach, Karen L.,Liu, Shenping,Marfat, Anthony,McAllister, Laura,McElroy, Eric,Menard, Carol A.,Mitton-Fry, Mark,Mullins, Lisa,Noe, Mark C.,O'Donnell, John,Oliver, Robert,Penzien, Joseph,Plummer, Mark,Shanmugasundaram, Veerabahu,Thoma, Christy,Tomaras, Andrew P.,Uccello, Daniel P.,Vaz, Alfin,Wishka, Donn G.

, p. 1662 - 1670 (2012/04/17)

The synthesis and biological activity of a new series of LpxC inhibitors represented by pyridone methylsulfone hydroxamate 2a is presented. Members of this series have improved solubility and free fraction when compared to compounds in the previously described biphenyl methylsulfone hydroxamate series, and they maintain superior Gram-negative antibacterial activity to comparator agents.

N-LINKED HYDROXAMIC ACID DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS

-

, (2011/07/07)

The present invention is directed to a new class of hydroxamic acid derivatives, their use as LpxC inhibitors, and more specifically their use to treat bacterial infections. Formula (I).

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