1312612-74-0

Basic information

• Product Name: 4-[2-(4-aminophenyl)ethyl]benzoic acid tert-butyl ester
• Synonyms: 4-[2-(4-aminophenyl)ethyl]benzoic acid tert-butyl ester
• CAS NO: 1312612-74-0
• Molecular Weight: 297.397
• Mol File: 1312612-74-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-[2-(4-aminophenyl)ethyl]benzoic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[2-(4-aminophenyl)ethyl]benzoic acid tert-butyl ester(1312612-74-0)
• EPA Substance Registry System: 4-[2-(4-aminophenyl)ethyl]benzoic acid tert-butyl ester(1312612-74-0)

Safety Data

• Hazardous Substances Data: 1312612-74-0(Hazardous Substances Data)

Upstream product

• 99-94-5 p-Toluic acid 
• 118537-46-5 {[4-(t-butoxycarbonyl)phenyl]methyl}triphenylphosphonium bromide 
• 108052-76-2 4-(bromomethyl)benzoic acid 1,1-dimethylethyl ester 
• 13756-42-8 tert-butyl 4-methylbenzoate 
• 1312612-73-9 4-[2-(4-nitrophenyl)ethenyl]benzoic acid tert-butyl ester 

Downstream Products

• 1312612-75-1 4-{2-[4-(1,3-dioxo-1,3-dihydroisoindol-2-yl)phenyl]ethyl}benzoic acid tert-butyl ester 
• 1312612-72-8 4-{2-[4-(1,3-dioxo-1,3-dihydroisoindol-2-yl)phenyl]ethyl}benzoic acid 

Relevant articles and documents

Peroxisome proliferator-activated receptor agonists with phenethylphenylphthalimide skeleton derived from thalidomide-related liver X receptor antagonists: Relationship between absolute configuration and subtype selectivity

Introduction of an alkylcarboxylic acid unit, which is a partial structure of endogenous peroxisome proliferator-activated receptor (PPAR) ligands, into a phenethylphenylphthalimide skeleton, which possesses liver X receptor (LXR) antagonistic activity, afforded novel PPAR ligands. The results of structure-activity relationship analysis and docking studies led us to the potent PPAR agonists 13c-e. The absolute configuration of 13c-e affects the PPAR subtype selectivity.