1312690-35-9

Upstream product

• 40615-36-9 4,4'-dimethoxytrityl chloride 
• 58-61-7 adenosine 
• 211617-72-0 (2-{[tris(propan-2-yl)silyl]oxy}phenyl)methanol 
• 90-01-7 salicylic alcohol 
• 13154-24-0 triisopropylsilyl chloride 
• 1312690-34-8 N₆-{{{2-[(triisopropylsilyl)oxy]benzyl}oxy}carbonyl}-5'-O-(4,4'-dimethoxytrityl)-adenosine 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 1312690-30-4 N₆-{{{2-[(triisopropylsilyl)oxy]benzyl}oxy}carbonyl}-5'-O-(4,4'-dimethoxytrityl)-2',3'-bis-O-acetyl-adenosine 
• 151928-74-4 5'-O-(4,4'-dimethoxytrityl)-2',3'-bis-O-acetyl-adenosine 
• 57018-82-3 5'-O-dimethoxytrityladenosine 

Relevant academic research and scientific papers

Synthesis and preliminary evaluation of pro-RNA 2′- O -masked with biolabile pivaloyloxymethyl groups in an RNA interference assay

The cellular delivery of bioactive nucleic acid-based drugs such as small interfering RNA (siRNA) represents a major technical hurdle for their pharmaceutical application. Prodrug-like approaches provide an attractive concept to address the delivery probl