131270-17-2Relevant academic research and scientific papers
General synthesis of enantiomerically pure β-amino acids
Gmeiner
, p. 5717 - 5720 (1990)
An efficient method for the synthesis of chiral β-amino acids starting from (S)-asparagine is shown. The key intermediate is an activated β-homoserine equivalent, which can be reacted with organocuprates to yield β-N,N-dibenzylamino nitrite derivatives. After deprotection the β-amino acids are obtained enantiomerically pure in high overall yield.
