1312703-30-2

Basic information

• Product Name: dimethyl 2’-amino-1,1’:4,1’’-terphenyl-4,4’’-dicarboxylate
• Synonyms: dimethyl 2’-amino-1,1’:4,1’’-terphenyl-4,4’’-dicarboxylate
• CAS NO: 1312703-30-2
• Molecular Weight: 361.397
• Mol File: 1312703-30-2.mol
• Article Data: 20

Chemical Properties

• CAS DataBase Reference: dimethyl 2’-amino-1,1’:4,1’’-terphenyl-4,4’’-dicarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: dimethyl 2’-amino-1,1’:4,1’’-terphenyl-4,4’’-dicarboxylate(1312703-30-2)
• EPA Substance Registry System: dimethyl 2’-amino-1,1’:4,1’’-terphenyl-4,4’’-dicarboxylate(1312703-30-2)

Safety Data

• Hazardous Substances Data: 1312703-30-2(Hazardous Substances Data)

Upstream product

• 3638-73-1 2,5-dibromoaniline 
• 99768-12-4 4-methoxycarbonylphenylboronic acid 

Downstream Products

• 1312703-28-8 2’-amino-1,1’:4,1’’-terphenyl-4,4’’-dicarboxylic acid 

Relevant articles and documents

A drug-loaded nanoscale metal-organic framework with a tumor targeting agent for highly effective hepatoma therapy

Drug delivery systems with targeting agents for precise drug release in cancer therapy are very significant and important. Herein, we report the rational design and synthesis of a DOX (doxorubicin) loaded UiO-68-type of nanoscale metal-organic framework (NMOF) with a tumor targeting agent (folic acid, FA), DOX@UiO-68-FA (3), as a multifunctional drug delivery system for hepatoma (Hep G2) therapy via tail-vein injection. Compared to free DOX, FA-unloaded DOX@Mi-UiO-68 (2), 3 exhibits a much higher antitumor efficacy, which was confirmed by cell imaging, standard 3-(4,5-dimethylthiahiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) proliferation and in vivo experiments.

Crystalline Nanochannels with Pendant Azobenzene Groups: Steric or Polar Effects on Gas Adsorption and Diffusion?

An azobenzene-containing, zirconium-based metal-organic framework (AzoMOF), upon irradiation with ultraviolet (UV) light at 365 ± 10 nm, underwent trans-to-cis isomerization of its azobenzene pendants to furnish the cis-isomer content of 21% (AzoMOF21%) in 30 min at the photostationary state and underwent backward isomerization into AzoMOF1% upon either irradiation with visible light (420-480 nm) or heating. When the cis-isomer content increased, the diffusion rate and amount of CO2 adsorbed into the nanochannels of AzoMOF decreased considerably. When erythrosine B, a polarity-probing guest, was used, it showed a red shift upon exposure of AzoMOF20%?EB to visible light, indicating that the interior environment of AzoMOF turns less polar as the trans-isomer content becomes higher. In sharp contrast, the adsorption profiles of AzoMOF15% and AzoMOF1% for Ar having an analogous kinetic diameter to CO2 but no quadrupole moment and a smaller polarizability were virtually identical to one another. Therefore, it is likely that CO2 experiences a dominant effect of a polar effect rather than a steric effect in the crystalline nanochannels.

Amino Acid-Functionalized Metal-Organic Frameworks for Asymmetric Base–Metal Catalysis

We report a strategy to develop heterogeneous single-site enantioselective catalysts based on naturally occurring amino acids and earth-abundant metals for eco-friendly asymmetric catalysis. The grafting of amino acids within the pores of a metal-organic framework (MOF), followed by post-synthetic metalation with iron precursor, affords highly active and enantioselective (>99 % ee for 10 examples) catalysts for hydrosilylation and hydroboration of carbonyl compounds. Impressively, the MOF-Fe catalyst displayed high turnover numbers of up to 10 000 and was recycled and reused more than 15 times without diminishing the enantioselectivity. MOF-Fe displayed much higher activity and enantioselectivity than its homogeneous control catalyst, likely due to the formation of robust single-site catalyst in the MOF through site-isolation.

Metal-organic frameworks containing nitrogen-donor ligands for efficient catalytic organic transformations

Metal-organic framework (MOFs) compositions based on nitrogen donor-based organic bridging ligands, including ligands based on 1,3-diketimine (NacNac), bipyridines and salicylaldimine, were synthesized and then post-synthetically metalated with metal precursors, such as complexes of first row transition metals. Metal complexes of the organic bridging ligands could also be directly incorporated into the MOFs. The MOFs provide a versatile family of recyclable and reusable single-site solid catalysts for catalyzing a variety of asymmetric organic transformations. The solid catalysts can also be integrated into a flow reactor or a supercritical fluid reactor.