1312707-17-7Relevant articles and documents
Iodine mediated intramolecular C2-amidative cyclization of indoles: A facile access to indole fused tetracycles
Badigenchala, Sindhura,Rajeshkumar, Venkatachalam,Sekar, Govindasamy
, p. 2297 - 2305 (2016)
A novel and metal-free I2-mediated intramolecular C2 amidation of indoles under mild reaction conditions is developed. This methodology affords various indole fused tetracyclic compounds, such as benzo[4,5]imidazo[1,2-a]indoles by intramolecular C2 amidation of N-aryl substituted indoles. This C2 sulfonamidative cyclization also offers convenient access to indolo[2,3-b]indoles and dihydroindolo[2,3-b]quinoline from C3 aryl substituted indoles in good to excellent yields. Indolo[2,3-b]quinolines are also synthesized by the domino cyclization-detosylation-aromatization reaction sequence.
Visible light-induced aerobic oxyamidation of indoles: A photocatalytic strategy for the preparation of tetrahydro-5H-indolo[2,3-b]quinolinols
An, Jing,Zou, You-Quan,Yang, Qing-Qing,Wang, Qiang,Xiao, Wen-Jing
supporting information, p. 1483 - 1489 (2013/07/04)
A visible light-induced, aerobic oxyamidation reaction of indoles, using air as the sole oxidant, has been developed. This process serves as a photocatalytic strategy to generate efficiently tetrahydro-5H-indolo[2,3-b] quinolinols, which may have interesting biological and pharmacological activities owing to their privileged indoline structure. Copyright
Direct annulation and alkylation of indoles with 2-aminobenzyl alcohols catalyzed by TFA
Robertson, Forest J.,Kenimer, Bradshaw D.,Wu, Jimmy
experimental part, p. 4327 - 4332 (2011/07/29)
An efficient method for the annulation of indoles with 2-aminobenzyl alcohols, catalyzed by TFA, to furnish 5,6-fused indoline aminals is reported. This method can be extended to the alkylation of indoles at C3. 2-Aminobenzyl alcohols are used directly without recourse to protection of the aniline nitrogen or activation of the alcohol.
