2521-13-3

Basic information

• Product Name: 5-METHOXY-1-METHYL-1H-INDOLE
• Synonyms: 5-Methoxy-1-methylindole;1-methyl-5-methoxyindole
• CAS NO: 2521-13-3
• Molecular Formula: C₁₀H₁₁NO
• Molecular Weight: 161.21
• Mol File: 2521-13-3.mol
• Article Data: 2

Chemical Properties

• Melting Point: 103-104 °C
• Boiling Point: 285.6°C at 760 mmHg
• Flash Point: 126.5°C
• Appearance: /
• Density: 1.06g/cm³
• Vapor Pressure: 0.00479mmHg at 25°C
• Refractive Index: 1.551
• Storage Temp.: Room temperature.
• CAS DataBase Reference: 5-METHOXY-1-METHYL-1H-INDOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-METHOXY-1-METHYL-1H-INDOLE(2521-13-3)
• EPA Substance Registry System: 5-METHOXY-1-METHYL-1H-INDOLE(2521-13-3)

Safety Data

• Hazardous Substances Data: 2521-13-3(Hazardous Substances Data)

Usage

General Description

5-Methoxy-1-methyl-1H-indole, also known as 5-Methoxy-1-methylindole, is a chemical compound with the molecular formula C11H11NO. It is categorized under the class of indoles, which are organic compounds containing a benzopyrrole ring system. There isn't much information available about specific properties or uses of 5-Methoxy-1-methyl-1H-indole, however, indoles on a broader scale are fundamental structures in biochemistry, chemistry, and pharmacology. They serve as key elements in important bio-active molecules like serotonin, melatonin and tryptophan, and are also used in the synthesis of a myriad of drugs.

InChI:InChI=1/C10H11NO/c1-11-6-5-8-7-9(12-2)3-4-10(8)11/h3-7H,1-2H3

Upstream product

• 94493-20-6 tetramethylviolacein 
• 74492-43-6 5-methoxy-1-methylindoline 

Downstream Products

• 13523-92-7 1-methyl-1H-indol-5-ol 
• 117616-09-8 5-methoxy-1-methyl-2-phenyl-1H-indole 
• 1229291-54-6 2-((R)-((R)-5,5-dimethyltetrahydrofuran-2-yl)(5-methoxy-1-methyl-1H-indol-3-yl)methyl)phenol 
• 144265-42-9 <(5-Methoxy-1-methyl)indol-2-yl>carbaldehyde 
• 1334225-11-4 benzyl 5-methoxy-1-methyl-1H-indole-3-carboxylate 
• 1315455-89-0 4-(5-methoxy-1-methyl-1H-indol-3-yl)-2-(methoxycarbonyl)-4-phenylbutanoic acid 
• 1315258-00-4 N-(3-chloro-5-methoxy-1-methyl-1H-indol-2-yl)-N,4-dimethylbenzenesulfonamide 
• 1315257-86-3 N-(5-methoxy-1-methyl-1H-indol-2-yl)-N,4-dimethylbenzenesulfonamide 
• 1239323-06-8 1-methylindolin-5-yl 4-isopropylphenylcarbamate 
• 1369581-95-2 3-(2-bromobenzoyl)-5-methoxy-1-methyl-1H-indole 

Relevant articles and documents

Hybrid Catalysis Enabling Room-Temperature Hydrogen Gas Release from N-Heterocycles and Tetrahydronaphthalenes

Hybrid catalyst systems to achieve acceptorless dehydrogenation of N-heterocycles and tetrahydronaphthalenes-model substrates for liquid organic hydrogen carriers-were developed. A binary hybrid catalysis comprising an acridinium photoredox catalyst and a Pd metal catalyst was effective for the dehydrogenation of N-heterocycles, whereas a ternary hybrid catalysis comprising an acridinium photoredox catalyst, a Pd metal catalyst, and a thiophosphoric imide organocatalyst achieved dehydrogenation of tetrahydronaphthalenes. These hybrid catalyst systems allowed for 2 molar equiv of H2 gas release from six-membered N-heterocycles and tetrahydronaphthalenes under mild conditions, i.e., visible light irradiation at rt. The combined use of two or three different catalyst types was essential for the catalytic activity.