2521-13-3

Basic information

• Product Name: 5-METHOXY-1-METHYL-1H-INDOLE
• Synonyms: 5-Methoxy-1-methylindole;1-methyl-5-methoxyindole
• CAS NO: 2521-13-3
• Molecular Formula: C₁₀H₁₁NO
• Molecular Weight: 161.21
• Mol File: 2521-13-3.mol

Chemical Properties

• Melting Point: 103-104 °C
• Boiling Point: 285.6°C at 760 mmHg
• Flash Point: 126.5°C
• Appearance: /
• Density: 1.06g/cm³
• Vapor Pressure: 0.00479mmHg at 25°C
• Refractive Index: 1.551
• Storage Temp.: Room temperature.
• CAS DataBase Reference: 5-METHOXY-1-METHYL-1H-INDOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-METHOXY-1-METHYL-1H-INDOLE(2521-13-3)
• EPA Substance Registry System: 5-METHOXY-1-METHYL-1H-INDOLE(2521-13-3)

Safety Data

• Hazardous Substances Data: 2521-13-3(Hazardous Substances Data)

Usage

Uses

Used in Biochemistry and Pharmacology:
5-Methoxy-1-methyl-1H-indole is used as a key component in the synthesis of various bio-active molecules for [application reason]. Indoles, in general, are essential in the formation of important compounds such as serotonin, melatonin, and tryptophan, which play crucial roles in biological processes.
Used in Drug Synthesis:
5-Methoxy-1-methyl-1H-indole is used as a building block in the development of new drugs for [application reason]. The indole structure is a common feature in many pharmaceutical compounds, making it a valuable component in drug synthesis and design.
Used in Chemical Research:
5-Methoxy-1-methyl-1H-indole is used as a subject of study in chemical research for [application reason]. The indole class of compounds offers a rich field for exploration, with potential for discovering new reactions, properties, and applications in various industries.

InChI:InChI=1/C10H11NO/c1-11-6-5-8-7-9(12-2)3-4-10(8)11/h3-7H,1-2H3

Upstream product

• 94493-20-6 tetramethylviolacein 
• 74492-43-6 5-methoxy-1-methylindoline 

Downstream Products

• 13523-92-7 1-methyl-1H-indol-5-ol 
• 128984-34-9 (2R,3R)-2-Benzyloxycarbonylamino-3-(5-methoxy-1-methyl-1H-indol-3-yl)-butyric acid 
• 934479-36-4 (R)-2-(5-methoxy-1-methyl-1H-indol-3-yl)-2-phenylethanol 
• 934478-93-0 (R)-5-methoxy-1-methyl-3-(1-phenyl-2-(prop-2-ynyloxy)ethyl)-1H-indole 
• 934478-96-3 (R)-3-(2-(but-2-ynyloxy)-1-phenylethyl)-5-methoxy-1-methyl-1H-indole 
• 117616-09-8 5-methoxy-1-methyl-2-phenyl-1H-indole 
• 1207189-33-0 C₂₂H₂₁NO₂ 
• 1229291-54-6 2-((R)-((R)-5,5-dimethyltetrahydrofuran-2-yl)(5-methoxy-1-methyl-1H-indol-3-yl)methyl)phenol 

Relevant articles and documents

Hybrid Catalysis Enabling Room-Temperature Hydrogen Gas Release from N-Heterocycles and Tetrahydronaphthalenes

Hybrid catalyst systems to achieve acceptorless dehydrogenation of N-heterocycles and tetrahydronaphthalenes-model substrates for liquid organic hydrogen carriers-were developed. A binary hybrid catalysis comprising an acridinium photoredox catalyst and a Pd metal catalyst was effective for the dehydrogenation of N-heterocycles, whereas a ternary hybrid catalysis comprising an acridinium photoredox catalyst, a Pd metal catalyst, and a thiophosphoric imide organocatalyst achieved dehydrogenation of tetrahydronaphthalenes. These hybrid catalyst systems allowed for 2 molar equiv of H2 gas release from six-membered N-heterocycles and tetrahydronaphthalenes under mild conditions, i.e., visible light irradiation at rt. The combined use of two or three different catalyst types was essential for the catalytic activity.

SPECTROSCOPIC PROPERTIES OF VIOLACEIN AND RELATED COMPOUNDS: CRYSTAL STRUCTURE OF TETRAMETHYLVIOLACEIN

Violacein and deoxyviolacein have been isolated from cultures of Alteromonas Luteoviolacea.The violacein-type lactams (1) and lactones (3) have a merocyanine chromophore which was confirmed by the effects of substituents on the visible spectra and by HMO calculations.Using parameters derived from an X-ray crystal structure analysis of tetramethylviolacein, PPP calculations of the electronic spectra of violacein and isoviolacein derivatives showed good agreement with observed values.