1312772-35-2

Basic information

• Product Name: methyl [(2S)-1-(benzyloxy)-3-hydroxy-2-methylpropan-2-yl]carbamate
• Synonyms: methyl [(2S)-1-(benzyloxy)-3-hydroxy-2-methylpropan-2-yl]carbamate
• CAS NO: 1312772-35-2
• Molecular Weight: 253.298
• Mol File: 1312772-35-2.mol

Chemical Properties

• CAS DataBase Reference: methyl [(2S)-1-(benzyloxy)-3-hydroxy-2-methylpropan-2-yl]carbamate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl [(2S)-1-(benzyloxy)-3-hydroxy-2-methylpropan-2-yl]carbamate(1312772-35-2)
• EPA Substance Registry System: methyl [(2S)-1-(benzyloxy)-3-hydroxy-2-methylpropan-2-yl]carbamate(1312772-35-2)

Safety Data

• Hazardous Substances Data: 1312772-35-2(Hazardous Substances Data)

Upstream product

• 116842-10-5 (2R,4S)-(-)-Dimethyl-2-(1,1-dimethylethyl)-3,4-oxazolidindicarboxylat 

Downstream Products

• 1618092-44-6 (4R)-4-[(E)-2-(2,4-dimethylphenyl)ethenyl]-4-methyl-1,3-oxazolidin-2-one 
• 1618092-43-5 {[(4S)-4-methyl-2-oxo-1,3-oxazolidin-4-yl]methyl}(triphenyl)phosphonium iodide 
• 1618092-42-4 {[(4S)-4-methyl-2-oxo-1,3-oxazolidin-4-yl]methyl}(triphenyl)phosphonium iodide 
• 1043491-17-3 (4R)-4-methyl-4-(2-phenylethyl)-4,5-dihydro-1,3-oxazol-2-amine 
• 1618092-57-1 (4R)-4-(2-{2-chloro-4-[(3-methoxyphenyl)sulfanyl]phenyl}ethyl)-4-methyl-1,3-oxazolidin-2-one 
• 1618092-56-0 (4R)-4-[(E)-2-{2-chloro-4-[(3-methoxyphenyl)sulfanyl]phenyl}ethenyl]-4-methyl-1,3-oxazolidin-2-one 
• 1618092-55-9 (4R)-4-{(E)-2-[4-(heptyloxy)phenyl]vinyl}-4-methyl-1,3-oxazolidin-2-one 
• 827344-01-4 (4R)-4-methyl-4-[(E)-2-(1-methyl-1H-pyrrol-2-yl)ethenyl]-1,3-oxazolidin-2-one 
• 1618092-47-9 (4R)-4-[(E)-2-(4-dimethylaminophenyl)ethenyl]-4-methyl-1,3-oxazolidin-2-one 
• 1618092-46-8 (4R)-4-[(E)-2-(2,4,6-trimethoxylphenyl)ethenyl]-4-methyl-1,3-oxazolidin-2-one 
• 1618092-45-7 methyl 2-{(E)-2-[(4R)-4-methyl-2-oxo-1,3-oxazolidin-4-yl]ethenyl}benzoate 

Relevant articles and documents

Synthesis of a chiral phosphonium salt for the preparation of α-substituted alaninol derivatives

We herein report the synthesis of a chiral phosphonium salt, {[(4S)-4-methyl-2-oxo-1,3-oxazolidin-4-yl]methyl}(triphenyl)phosphonium iodide 13 to provide a new Wittig reagent for the general method of synthesizing α-substituted alaninol derivatives. Our method described here is widely applicable to reactions with various types of aldehyde to afford olefin products with high E-selectivity, enabling us to provide a new approach to the synthesis of chiral S1P1 agonists including our key intermediates, and of the trace amine-associated receptor 1 (TAAR1) agonist.

Synthesis of a chiral phosphonium salt for the preparation of α-substituted alaninol derivatives

We herein report the synthesis of a chiral phosphonium salt, {[(4S)-4-methyl-2-oxo-1,3-oxazolidin-4-yl]methyl}(triphenyl)phosphonium iodide 13 to provide a new Wittig reagent for the general method of synthesizing α-substituted alaninol derivatives. Our method described here is widely applicable to reactions with various types of aldehyde to afford olefin products with high E-selectivity, enabling us to provide a new approach to the synthesis of chiral S1P1agonists including our key intermediates, and of the trace amine-associated receptor 1 (TAAR1) agonist.

Asymmetric synthesis of α,α-disubstituted α-amino alcohol derivatives

Herein we report the asymmetric synthesis of α,α-disubstituted α-amino alcohol derivatives 22, 25 and 26, key intermediates of a novel immunomodulator, using Seebach's method. This synthetic method can be applied to the large scale synthesis of chiral sph