1312781-60-4Relevant academic research and scientific papers
Design and synthesis of an ER-specific fluorescent probe based on carboxylesterase activity with quinone methide cleavage process
Hakamata, Wataru,MacHida, Aki,Oku, Tadatake,Nishio, Toshiyuki
, p. 3206 - 3209 (2011)
CEs are important enzymes that catalyze the hydrolysis of prodrugs. In this Letter, we present a new mechanistic ER-specific fluorescent probe 1 based on CE activity. Permeation of 1 into cells and subsequent hydrolytic activation by CEs causes spontaneou
