126070-20-0

Basic information

• Product Name: 4-(((Tert-Butyldimethylsilyl)Oxy)Methyl)Phenol
• Synonyms: 4-(((Tert-Butyldimethylsilyl)Oxy)Methyl)Phenol;Phenol, 4-[[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-;4-(((tert-butyldimethylsilyl)oxy)methyl)phenol(WXC04509)
• CAS NO: 126070-20-0
• Molecular Formula: C₁₃H₂₂O₂Si
• Molecular Weight: 238.39808
• Mol File: 126070-20-0.mol
• Article Data: 43

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-(((Tert-Butyldimethylsilyl)Oxy)Methyl)Phenol(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(((Tert-Butyldimethylsilyl)Oxy)Methyl)Phenol(126070-20-0)
• EPA Substance Registry System: 4-(((Tert-Butyldimethylsilyl)Oxy)Methyl)Phenol(126070-20-0)

Safety Data

• Hazardous Substances Data: 126070-20-0(Hazardous Substances Data)

Upstream product

• 117635-46-8 1-(tert-butyldimethylsilyloxy)-4-((tert-butyldimethylsilyloxy)methyl)benzene 
• 1114567-57-5 C₂₉H₄₀O₂Si₂ 
• 87736-74-1 4-(tert-butyldimethylsiloxymethyl)bromobenzene 
• 1393446-12-2 tert-butyl((4-(dimethylsilyl)benzyl)oxy)dimethylsilane 
• 623-05-2 (4-hydroxyphenyl)methanol 
• 1228447-97-9 tert-butyl(4-(iso-propoxydimethylsilyl)benzyloxy)dimethylsilane 
• 1198597-47-5 C₂₂H₄₂O₂Si₂ 
• 1058019-24-1 C₁₆H₂₄O₂Si 
• 288-32-4 1H-imidazole 
• 18162-48-6 tert-butyldimethylsilyl chloride 

Downstream Products

• 70362-64-0 4-(hydroxymethyl)phenyl isobutyrate 
• 658053-71-5 4-(2,5-dioxo-2,5-dihydro-pyrrol-1-yl)-butanoic acid 4-tert-butyldimethylsilanyloxymethyl-phenyl ester 
• 899799-91-8 (S)-3-(4-((tert-butyldimethylsilyloxy)methyl)phenoxy)-dihydrofuran-2(3H)-one 
• 848004-48-8 C₂₅H₃₇NO₇Si 
• 1202249-33-9 4-(((tert-butyldimethylsilyl)oxy)methyl)phenyl (4-nitrophenyl)carbonate 
• 207679-81-0 (R)-2-[3-(diisopropylamino)-1-phenylpropyl]-4-(hydroxymethyl)-phenol 
• 200801-70-3 RS-N,N-diisopropyl-3-(2-hydroxy-5-(hydroxymethyl)phenyl)-3-phenylpropylamine 
• 959624-43-2 [2-(4-methylpiperazin-1-yl)-4-phenyl-chroman-6-yl]-methanol 
• 959624-24-9 (2-hydroxy-4-phenyl-3,4-dihydro-2H-chromen-6-yl)methanol 
• 1333234-72-2 (R)-2-[3-(diisopropylamino)-1-phenylpropyl]-4-(hydroxymethyl)phenol (R)-2-acetoxy(phenyl)acetate 

Relevant articles and documents

Photochemical Amplifier Based on Self-Immolative Dendritic Spacers

A self-immolative dendritic structure was synthesized. It is based on phenol derivatives with three hydroxymethyl arms at both ortho and para positions of the core unit, potentially releasing up to 27 leaving groups in a third-generation dendrimer. The tr

COMPOUNDS COMPRISING CLEAVABLE LINKER AND USES THEREOF

Provided are a compound including a cleavable linker, a use thereof, and an intermediate compound for preparing the same, and more particularly, the compound including a cleavable linker of the present invention may include an active agent (for example, a drug, a toxin, a ligand, a probe for detection, etc.) having a specific function or activity, a -S(=0)(=N-)- functional group which is capable of selectively releasing the active agent, and a functional group which triggers a chemical reaction, a physicochemical reaction and/or a biological reaction by external stimulation, and may further include a ligand (for example, oligopeptide, polypeptide, antibody, etc.) having binding specificity for a desired target receptor.

COMPOSITIONS COMPRISING ENZYME CLEAVABLE LINKER PLATFORMS AND CONJUGATES THEREOF

The present invention relates to a cleavable linker platform. In particular, the invention relates to construction of an enzyme cleavable linker platform conjugated to a drug or a diagnostically relevant compound, a biomolecule, and an enzyme cleavable group, for which cleavage of the enzyme cleavable group leads to release of the drug or diagnostically relevant compound.