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4-(((Tert-Butyldimethylsilyl)Oxy)Methyl)Phenol is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 126070-20-0 Structure
  • Basic information

    1. Product Name: 4-(((Tert-Butyldimethylsilyl)Oxy)Methyl)Phenol
    2. Synonyms: 4-(((Tert-Butyldimethylsilyl)Oxy)Methyl)Phenol;Phenol, 4-[[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-;4-(((tert-butyldimethylsilyl)oxy)methyl)phenol(WXC04509)
    3. CAS NO:126070-20-0
    4. Molecular Formula: C13H22O2Si
    5. Molecular Weight: 238.39808
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 126070-20-0.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 4-(((Tert-Butyldimethylsilyl)Oxy)Methyl)Phenol(CAS DataBase Reference)
    10. NIST Chemistry Reference: 4-(((Tert-Butyldimethylsilyl)Oxy)Methyl)Phenol(126070-20-0)
    11. EPA Substance Registry System: 4-(((Tert-Butyldimethylsilyl)Oxy)Methyl)Phenol(126070-20-0)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 126070-20-0(Hazardous Substances Data)

126070-20-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 126070-20-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,6,0,7 and 0 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 126070-20:
(8*1)+(7*2)+(6*6)+(5*0)+(4*7)+(3*0)+(2*2)+(1*0)=90
90 % 10 = 0
So 126070-20-0 is a valid CAS Registry Number.

126070-20-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-[[tert-butyl(dimethyl)silyl]oxymethyl]phenol

1.2 Other means of identification

Product number -
Other names 4-(((tert-butyldimethylsilyl)oxy)methyl)phenol

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:126070-20-0 SDS

126070-20-0Relevant articles and documents

Photochemical Amplifier Based on Self-Immolative Dendritic Spacers

Kastrati, Agonist,Bochet, Christian G.

, p. 7776 - 7785 (2019)

A self-immolative dendritic structure was synthesized. It is based on phenol derivatives with three hydroxymethyl arms at both ortho and para positions of the core unit, potentially releasing up to 27 leaving groups in a third-generation dendrimer. The tr

Selective deprotection of silyl-protected phenols using solid NaOH and a phase transfer catalyst

Crouch, R. David,Stieff, Mike,Frie, Jessica L.,Cadwallader, Amy B.,Bevis, Daniel C.

, p. 3133 - 3136 (1999)

Aryl silyl ethers can be deprotected to yield phenols in good to excellent yields using a biphasic system of 10 equivalents of NaOH and catalytic Bu4NHSO4 in 1,4-dioxane. Alkyl silyl ethers prepared using a variety of silyl protecting groups survive under these conditions, allowing selective deprotection of silyl-protected phenols in the presence of silyl- protected alcohols.

COMPOUNDS COMPRISING CLEAVABLE LINKER AND USES THEREOF

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Page/Page column 175, (2020/09/03)

Provided are a compound including a cleavable linker, a use thereof, and an intermediate compound for preparing the same, and more particularly, the compound including a cleavable linker of the present invention may include an active agent (for example, a drug, a toxin, a ligand, a probe for detection, etc.) having a specific function or activity, a -S(=0)(=N-)- functional group which is capable of selectively releasing the active agent, and a functional group which triggers a chemical reaction, a physicochemical reaction and/or a biological reaction by external stimulation, and may further include a ligand (for example, oligopeptide, polypeptide, antibody, etc.) having binding specificity for a desired target receptor.

Fluorescent probe for detecting cysteine

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Paragraph 0016-0017, (2020/01/25)

The invention discloses a fluorescent probe for detecting cysteine. According to the invention, the fluorescent probe can identify and distinguish cysteine from various amino acids and some common substances; when the probe acts with Cys, the fluorescence

COMPOSITIONS COMPRISING ENZYME CLEAVABLE LINKER PLATFORMS AND CONJUGATES THEREOF

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Page/Page column 72; 73, (2021/01/23)

The present invention relates to a cleavable linker platform. In particular, the invention relates to construction of an enzyme cleavable linker platform conjugated to a drug or a diagnostically relevant compound, a biomolecule, and an enzyme cleavable group, for which cleavage of the enzyme cleavable group leads to release of the drug or diagnostically relevant compound.

DOUBLE-HEADED PROTEASE INHIBITOR

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Paragraph 0975, (2020/09/17)

The present invention provides a compound that is highly safe and useful in the prevention, alleviation, and/or treatment of various diseases involving enteropeptidase inhibition and/or trypsin inhibition, a pharmaceutical composition containing the compo

ANTICANCER AGENT DELIVERY MOLECULE

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Paragraph 0220-0222, (2017/08/04)

PROBLEM TO BE SOLVED: To provide a compound which can be used as an anticancer agent targeting a cancer cell that highly expresses Lysine-specific demethylase 1 (LSD1) or salt thereof. SOLUTION: The present invention provides a compound represented by the following formula (I) or a pharmaceutically acceptable salt thereof, where Ar, R1, R2, L, Z, p, q, *1 and *2 are as defined in the specifications. SELECTED DRAWING: None COPYRIGHT: (C)2017,JPOandINPIT

LYMPH DIRECTING PRODRUGS

-

Page/Page column 85; 86, (2016/02/29)

H:\dar\Interwoven\NRPortbl\DCC\DAR\8230712_1.doc-12/08/2015 Abstract The present invention relates to compounds and their uses, in particular, compounds in the form of prodrugs that promote transport of a pharmaceutical agent to the lymphatic system and subsequently enhance release of the parent drug.

Conformational Constraint of the Glycerol Moiety of Lysophosphatidylserine Affords Compounds with Receptor Subtype Selectivity

Jung, Sejin,Inoue, Asuka,Nakamura, Sho,Kishi, Takayuki,Uwamizu, Akiharu,Sayama, Misa,Ikubo, Masaya,Otani, Yuko,Kano, Kuniyuki,Makide, Kumiko,Aoki, Junken,Ohwada, Tomohiko

, p. 3750 - 3776 (2016/05/19)

Lysophosphatidylserine (LysoPS) is an endogenous lipid mediator that specifically activates membrane proteins of the P2Y and its related families of G protein-coupled receptors (GPCR), GPR34 (LPS1), P2Y10 (LPS2), and GPR174 (LPS3). Here, in order to increase potency and receptor selectivity, we designed and synthesized LysoPS analogues containing the conformational constraints of the glycerol moiety. These reduced structural flexibility by fixation of the glycerol framework of LysoPS using a 2-hydroxymethyl-3-hydroxytetrahydropyran skeleton, and related structures identified compounds which exhibited high potency and selectivity for activation of GPR34 or P2Y10. Morphing of the structural shape of the 2-hydroxymethyl-3-hydroxytetrahydropyran skeleton into a planar benzene ring enhanced the P2Y10 activation potentcy rather than the GPR34 activation.

LYSOPHOSPHATIDYLSERINE DERIVATIVE

-

Paragraph 0239; 0241-0243, (2016/10/07)

PROBLEM TO BE SOLVED: To provide a lysophosphatidylserine derivative or salt thereof. SOLUTION: The present invention provides a lysophosphatidylserine derivative or salt thereof, or a pharmaceutical composition or lysophosphatidylserine receptor function modulator including the compound or salt thereof. SELECTED DRAWING: None COPYRIGHT: (C)2016,JPOandINPIT

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