1312938-83-2

Upstream product

• 100-46-9 benzylamine 
• 114772-54-2 4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile 
• 33524-79-7 1-benzyl-6-methyl-1,2,3,4-tetrahydropyridine-2,4-dione 

Downstream Products

• 1312938-59-2 3-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1-benz yl-4-butyl-6-methylpyridin-2(1H)-one 
• 1312939-06-2 C₃₀H₃₁N₃O₃ 
• 1312938-85-4 C₃₁H₃₃N₃O₂ 
• 1312938-84-3 4'-[(1-benzyl-4-butyl-6-methyl-2-oxo-1,2-dihydropyridin-3-yl)methyl]biphenyl-2-carbonitrile 
• 1312938-82-1 3-{4'-[(1-benzyl-6-methyl-2-oxo-4-propoxy-1,2-dihydro pyridin-3-yl)methyl]biphenyl-2-yl}-1,2,4-oxadiazol-5(4H)-one 
• 1312938-81-0 3-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1-benzyl-6-methyl-4-propoxypyridin-2(1H)-one 
• 1312938-60-5 3-{4'-[(1-benzyl-4-butyl-6-methyl-2-oxo-1,2-dihydropyridin-3-yl)methyl]biphenyl-2-yl}-1,2,4-oxadiazol-5(4H)-one 
• 1312939-05-1 4'-[(1-benzyl-6-methyl-2-oxo-4-propoxy-1,2-dihydropyridin-3-yl)methyl]biphenyl-2-carbonitrile 
• 1312939-07-3 C₂₈H₂₁F₃N₂O₄S 

Relevant academic research and scientific papers

NOVEL 2-PYRIDONE DERIVATIVE AND PHARMACEUTICAL PRODUCT CONTAINING SAME

Disclosed is a novel 2-pyridone derivative represented by general formula (1), which has both angiotensin II receptor antagonist activity and PPAR-3 activating activity and is useful as a prophylactic and/or therapeutic agent for cardiovascular diseases and metabolic diseases. Also disclosed is a pharmaceutical composition which contains the novel 2-pyridone derivative. In general formula (1), R1 represents a C1-6 alkyl group or a C1-6 alkoxy group; R2 represents a C1-6 alkyl group or a C3-8 cycloalkyl group; R3 represents a C1-6 alkyl group, a C6-10 aryl-C1-6 alkyl group, a C1-6 alkoxy-C1-6 alkyl group or a group represented by formula (2) (wherein A represents a nitrogen atom or CH, and R5 represents a hydrogen atom or a C1-6 alkoxy group); and R4 represents a group represented by formula (3) or (4).