1312943-79-5Relevant academic research and scientific papers
First total synthesis of tenuifolin via PIFA mediated oxidative biaryl coupling
Tang, Changhua,Li, Ziyuan,Wang, Yiyun,Xu, Jinyi,Kong, Lingyi,Yao, Hequan,Wu, Xiaoming
, p. 3275 - 3278 (2011/07/08)
The first total synthesis of a sesquiterpenoid, tenuifolin, was achieved in seven linear steps. Phenyliodine(III) bis(trifluoacetate) (PIFA) mediated oxidative biaryl coupling was employed as a key step to construct the central seven-membered ring with a double bond. The double bond formation was also exploited.
