13130-13-7

Basic information

• Product Name: 5-(3-NITRO-PHENYL)-FURAN-2-CARBOXYLIC ACID
• Synonyms: ASISCHEM T31188;ART-CHEM-BB B025355;AKOS BAR-1991;5-(3-NITRO-PHENYL)-FURAN-2-CARBOXYLIC ACID;5-(3-NITROPHENYL)-2-FURANCARBOXYLIC ACID;5-(3-NITROPHENYL)-2-FUROIC ACID;RARECHEM AL BE 0713
• CAS NO: 13130-13-7
• Molecular Formula: C₁₁H₇NO₅
• Molecular Weight: 233.18
• Product Categories: API intermediates
• Mol File: 13130-13-7.mol
• Article Data: 13

Chemical Properties

• Melting Point: 252-260 °C(lit.)
• Boiling Point: 450.2 °C at 760 mmHg
• Flash Point: 226.1 °C
• Appearance: /
• Density: 1.44 g/cm³
• Vapor Pressure: 6.83E-09mmHg at 25°C
• Refractive Index: 1.616
• PKA: 2.88±0.10(Predicted)
• CAS DataBase Reference: 5-(3-NITRO-PHENYL)-FURAN-2-CARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(3-NITRO-PHENYL)-FURAN-2-CARBOXYLIC ACID(13130-13-7)
• EPA Substance Registry System: 5-(3-NITRO-PHENYL)-FURAN-2-CARBOXYLIC ACID(13130-13-7)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• Hazardous Substances Data: 13130-13-7(Hazardous Substances Data)

Usage

General Description

5-(3-NITRO-PHENYL)-FURAN-2-CARBOXYLIC ACID is a chemical compound with a molecular formula C12H7NO5. It is a derivative of furan carboxylic acid, which is a heterocyclic compound. The presence of a nitro group in the phenyl ring makes this compound highly reactive and potentially useful in organic synthesis. It has the potential to be used in the synthesis of various pharmaceuticals and agrochemicals. The compound can also be used as a building block in the development of new materials and dyes. However, it is important to handle this compound with caution due to its reactivity and potential toxic properties.

InChI:InChI=1/C11H7NO5/c13-11(14)10-5-4-9(17-10)7-2-1-3-8(6-7)12(15)16/h1-6H,(H,13,14)

Upstream product

• 88-14-2 2-furanoic acid 
• 99-09-2 3-nitro-aniline 
• 98-01-1 furfural 
• 41019-37-8 5-(3-nitrophenyl)-furan-2-carboxylic acid methyl ester 
• 2527-99-3 methyl 5-bromo-2-furoate 
• 13331-27-6 m-nitrobenzene boronic acid 

Downstream Products

• 61941-87-5 5-(3-nitrophenyl)furan-2-carbonyl chloride 
• 1255501-42-8 N-(4-bromobenzoyl)-N'-[5-(3-nitrophenyl)-2-furoyl]hydrazine 
• 1274572-86-9 C₁₇H₁₈N₂O₆ 
• 1354698-13-7 N-5-(3'-nitrophenyl)-2-furoyl-1H-pyrazole 
• 54023-06-2 5-(3-amino-phenyl)-furan-2-carboxylic acid methyl ester 
• 942232-15-7 C₃₄H₃₈N₄O₆ 
• 528885-24-7 5-(3-(2-(5-cyclohexyl-1-(3,3-dimethyl-2-oxo-butyl)-2-oxo-1,2-dihydro-3H-1,3,4-benzotriazepin-3-yl)-acetylamino)-phenyl)-furan-2-carboxylic acid 
• 41019-37-8 5-(3-nitrophenyl)-furan-2-carboxylic acid methyl ester 
• 1026635-58-4 C₁₇H₁₁NO₇S 
• 1620099-68-4 2-[5-(3-nitrophen-1-yl)-furan-2-yl-carbonyl]-1,2,3,4 tetrahydro-β-carboline 
• 1557032-51-5 4-{cyclopropyl-[5-(3-nitro-phenyl)-furan-2-carbonyl]-amino}-piperidine-1-carboxylic acid tert-butyl ester 
• 1428422-62-1 3-{3-[5-(3-nitro-phenyl)-furan-2-ylmethylene]-2-oxo-2,3-dihydro-indol-1-ylmethyl}-benzoic acid 

Relevant articles and documents

Synthesis of some thiadiazolotriazinone derivatives as possible antimicrobial agents

A series of 7-substituted-3-t-butyl 4(H)-1,3,4-thiadiazolo(2,3-c)-1,2,4- triazine-4-one (3) have been synthesized by condensing 4-amino-6-t-butyl-3- mercapto-1,2,4-triazin-5(4H)-one (1) with substituted Arylfuroic acids (2) using POCl3 as a cyclizing agen

Discovery of a series of 5-phenyl-2-furan derivatives containing 1,3-thiazole moiety as potent Escherichia coli β-glucuronidase inhibitors

Gut microbial β-glucuronidases have drawn much attention due to their role as a potential therapeutic target to alleviate some drugs or their metabolites-induced gastrointestinal toxicity. In this study, fifteen 5-phenyl-2-furan derivatives containing 1,3

Synthesis and SAR of 5-aryl-furan-2-carboxamide derivatives as potent urotensin-II receptor antagonists

The synthesis and biological evaluation as potential urotensin-II receptor antagonists of a series of 5-arylfuran-2-carboxamide derivatives 1, bearing a 4-(3-chloro-4-(piperidin-4-yloxy)benzyl)piperazin-1-yl group, are described. The results of a systemat