61941-87-5

Basic information

• Product Name: 5-(3-NITROPHENYL)FURAN-2-CARBONYL CHLORIDE
• Synonyms: 2-furancarbonyl chloride, 5-(3-nitrophenyl)-; 5-(3-Nitrophenyl)-2-furoyl chloride; 5-(3-nitrophenyl)furan-2-carbonyl chloride
• CAS NO: 61941-87-5
• Molecular Formula: C₁₁H₆ClNO₄
• Molecular Weight: 251.62
• Mol File: 61941-87-5.mol
• Article Data: 16

Chemical Properties

• Boiling Point: 408.1°C at 760 mmHg
• Flash Point: 200.6°C
• Appearance: /
• Density: 1.431g/cm³
• Vapor Pressure: 7.16E-07mmHg at 25°C
• Refractive Index: 1.597
• CAS DataBase Reference: 5-(3-NITROPHENYL)FURAN-2-CARBONYL CHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(3-NITROPHENYL)FURAN-2-CARBONYL CHLORIDE(61941-87-5)
• EPA Substance Registry System: 5-(3-NITROPHENYL)FURAN-2-CARBONYL CHLORIDE(61941-87-5)

Safety Data

• RIDADR: UN3261
• HazardClass: 8
• PackingGroup: III
• Hazardous Substances Data: 61941-87-5(Hazardous Substances Data)

Usage

General Description

5-(3-Nitrophenyl)furan-2-carbonyl chloride is an organic compound with the chemical formula C10H5ClNO4. It is a chlorinated derivative of furan-2-carbonyl chloride with a nitrophenyl group attached to the carbon at position 5. 5-(3-NITROPHENYL)FURAN-2-CARBONYL CHLORIDE is used in the synthesis of various pharmaceuticals and agrochemicals as a reagent in organic reactions. It is a powerful acylating agent and is usually handled and used with caution due to its reactivity and potential for causing skin and eye irritation.

InChI:InChI=1/C11H6ClNO4/c12-11(14)10-5-4-9(17-10)7-2-1-3-8(6-7)13(15)16/h1-6H

Upstream product

• 13130-13-7 5-(3-nitro-phenyl)-furan-2-carboxylic acid 
• 41019-37-8 5-(3-nitrophenyl)-furan-2-carboxylic acid methyl ester 
• 2527-99-3 methyl 5-bromo-2-furoate 
• 13331-27-6 m-nitrobenzene boronic acid 
• 99-09-2 3-nitro-aniline 
• 88-14-2 2-furanoic acid 

Downstream Products

• 140160-23-2 5-(3-Nitro-phenyl)-furan-2-carbonyl isothiocyanate 
• 146902-46-7 1-[5-(3-nitro-phenyl)-furan-2-carbonyl]-3-phenyl-thiourea 
• 41019-37-8 5-(3-nitrophenyl)-furan-2-carboxylic acid methyl ester 
• 1620099-68-4 2-[5-(3-nitrophen-1-yl)-furan-2-yl-carbonyl]-1,2,3,4 tetrahydro-β-carboline 
• 753499-70-6 (1,4-diaza-bicyclo[3.2.2]non-4-yl)-5-(3-nitrophenyl)-furan-2-yl-methanone 
• 1354698-13-7 N-5-(3'-nitrophenyl)-2-furoyl-1H-pyrazole 
• 1007552-01-3 C₁₆H₉ClN₂O₅ 

Relevant articles and documents

Discovery of a series of 5-phenyl-2-furan derivatives containing 1,3-thiazole moiety as potent Escherichia coli β-glucuronidase inhibitors

Gut microbial β-glucuronidases have drawn much attention due to their role as a potential therapeutic target to alleviate some drugs or their metabolites-induced gastrointestinal toxicity. In this study, fifteen 5-phenyl-2-furan derivatives containing 1,3

Synthesis and SAR of 5-aryl-furan-2-carboxamide derivatives as potent urotensin-II receptor antagonists

The synthesis and biological evaluation as potential urotensin-II receptor antagonists of a series of 5-arylfuran-2-carboxamide derivatives 1, bearing a 4-(3-chloro-4-(piperidin-4-yloxy)benzyl)piperazin-1-yl group, are described. The results of a systemat

Synthesis and biological evaluation of 2,5-disubstituted furan derivatives as P-glycoprotein inhibitors for Doxorubicin resistance in MCF-7/ADR cell

Multidrug resistance (MDR) is a tendency in which cells become resistant to structurally and mechanistically unrelated drugs, which is mediated by P-glycoprotein (P-gp). It is one of the noteworthy problems in cancer therapy. As one of the most important