13130-38-6

Basic information

• Product Name: ethyl 2-(acetylamino)-5-ethyl-3-thiophenecarboxylate
• Synonyms: ethyl 2-(acetylamino)-5-ethyl-3-thiophenecarboxylate
• CAS NO: 13130-38-6
• Molecular Formula: C₁₁H₁₅NO₃S
• Molecular Weight: 241.3067
• Mol File: 13130-38-6.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: ethyl 2-(acetylamino)-5-ethyl-3-thiophenecarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 2-(acetylamino)-5-ethyl-3-thiophenecarboxylate(13130-38-6)
• EPA Substance Registry System: ethyl 2-(acetylamino)-5-ethyl-3-thiophenecarboxylate(13130-38-6)

Safety Data

• Hazardous Substances Data: 13130-38-6(Hazardous Substances Data)

Upstream product

• 105-56-6 ethyl 2-cyanoacetate 
• 4507-13-5 ethyl 2-amino-5-ethylthiophene-3-carboxylate 
• 75-36-5 acetyl chloride 

Relevant articles and documents

Synthesis and antitumor activity of α-aminophosphonate derivatives containing thieno[2,3-d]pyrimidines

Abstract Two series of thieno[2,3-d]pyrimidine derivatives were designed and synthesized, in which bioactive α-aminophosphonate subunits were introduced at the N3 position through an NN bond connection. The in vitro cytotoxic activity of the novel compounds was tested against human esophageal carcinoma cells (EC109), human hepatocarcinoma cells (HepG2), human gastric carcinoma cells (MGC-803), respectively, by the MTT method. The evaluation results revealed that compounds 6mb, 6mf, 6mg, 6nd and 6nh exerted the most potent inhibition against HepG2, MGC-803 and EC109 cells, respectively. In particular, compound 6mg presented excellent inhibitory effect against HepG2 (91.2%) and MGC-803 (94.4%) cells.