131318-41-7Relevant academic research and scientific papers
A highly stereoselective synthesis of α-substituted cis-α,β-dibenzyl-γ-butyrolactones
Moritani,Fukushima,Ogiku,Ukita,Miyagishima,Iwasaki
, p. 2787 - 2790 (1993)
α-substituted cis-α,β-dibenzyl-γ-butyrolactones (1) were synthesized in good yields in a highly diastereoselective manner via electrophilic additions to the metal enolates β,γ-disubstituted α-benzyl-γ-butyrolactones (2) as a key step.
Stereoselective syntheses of cis- and trans-isomers of α-hydroxy-α,β-dibenzyl-γ-butyrolactone lignans: New syntheses of (±)-trachelogenin and (±)-guayadequiol
Moritani, Yasunori,Fukushima, Chiaki,Ukita, Tatsuzo,Miyagishima, Toshikazu,Ohmizu, Hiroshi,Iwasaki, Tameo
, p. 6922 - 6930 (2007/10/03)
Cis- and trans-isomers of α-hydroxy-α,β-dibenzyl-γ-butyrolactone lignans 1a,d-g and 2a,c,d were stereoselectively synthesized in good yields based on the electrophilic addition to the metal enolate of α-benzyl-γ-butyrolactone derivatives 1l-o and 3 as a key step. This method was applied to the syntheses of (±)-trachelogenin and (±)-guayadequiol, representative examples of the trans- and cis-isomers of α-hydroxy-α,β-dibenzyl-γ-butyrolactone lignan series.
A synthesis of α-substituted trans-α, β-dibenzyl-γ-butyrolactones: Diastereofacial differentiation in the electrophilic attack on the metal enolates of α, β-dibenzyl-γ-butyrolactones
Moritani, Yasunori,Ukita, Tatsuzo,Nishitani, Takashi,Seki, Masahiko,Iwasaki, Tameo
, p. 3615 - 3618 (2007/10/02)
α-Substituted trans-α, β-dibenzyl-γ-butyrolactones were synthesized in a diastereoselective manner by the reaction of the potassium enolates of α, β-dibenzyl-γbutyrolactones with electrophiles. The method was applied to the synthesis of (±)trachelogenin.
