1313197-46-4Relevant articles and documents
Design and synthesis of 1-(1-benzothiophen-7-yl)-1H-pyrazole, a novel series of G protein-coupled receptor 52 (GPR52) agonists
Nakahata, Takashi,Tokumaru, Kazuyuki,Ito, Yoshiteru,Ishii, Naoki,Setoh, Masaki,Shimizu, Yuji,Harasawa, Toshiya,Aoyama, Kazunobu,Hamada, Teruki,Kori, Masakuni,Aso, Kazuyoshi
, p. 1598 - 1608 (2018/02/27)
G-protein-coupled receptor 52 (GPR52) is classified as an orphan Gs-coupled G-protein-coupled receptor. GPR52 cancels dopamine D2 receptor signaling and activates dopamine D1/N-methyl-D-aspartate receptors via intracellular cAMP accumulation. Therefore, G