131326-39-1Relevant articles and documents
Enantioselectivity and diastereoselectivity in reductive radical cyclization reactions of 3-(ω-iodoalkylidene)-piperidin-2-ones
Dressel, Martina,Aechtner, Tobias,Bach, Thorsten
, p. 2206 - 2214 (2006)
The E-configurated 3-(ω-iodoalkylidene)-piperidin-2-ones 1a-e were prepared from the corresponding ω-tert-butyldimethylsilyloxyalkanals 5a-e by aldol condensation with N-tert-butyloxycarbonylpiperidone, subsequent silyl deprotection and iododehydroxylatio
Synthesis and application of monodisperse oligo(oxyethylene)-grafted polystyrene resins for solid-phase organic synthesis
Lumpi, Daniel,Braunshier, Christian,Horkel, Ernst,Hametner, Christian,Froehlich, Johannes
, p. 367 - 374 (2014)
In a preliminary investigation by our group, we found that poly(styrene-oxyethylene) graft copolymers (PS-PEG), for example, TentaGel resins, are advantageous for gel-phase 13C NMR spectroscopy. Because of the solution-like environment provided
PRODRUGS OF THE TYROSINE KINASE INHIBITOR FOR TREATING CANCER
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Paragraph 00157-00158, (2021/03/05)
There are provided compounds of Formula (I), and pharmaceutically acceptable salts and esters thereof, and pharmaceutical compositions thereof, useful for inhibition or modulation of the activity of tyrosine kinases and treatment of disease states or conditions mediated by tyrosine kinases, including cancers. (I)
KINASE INHIBITORS
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Paragraph 0676; 0677; 0678; 0679, (2017/10/27)
There are provided compounds of formula I, wherein T, A, Q, Z, G, R4, R5a, R5b and n have meanings given in the description, which compounds have antiinflammatory activity (e.g. through inhibition of one or more of members