131326-99-3

Usage

Uses

Used in Pharmaceutical Industry:
Ethanone, 1-(4-fluorophenyl)-2-[methyl(phenylmethyl)amino]is used as a precursor or intermediate in the synthesis of various drugs and pharmaceutical products. Its unique structure, including the fluorine and amino groups, contributes to its potential in the development of new medications and therapeutic agents.
Further research and studies on Ethanone, 1-(4-fluorophenyl)-2-[methyl(phenylmethyl)amino]- may reveal additional potential applications and properties in various fields, expanding its utility beyond the pharmaceutical industry.

Upstream product

• 131326-80-2 1-(4-Fluoro-phenyl)-2-[(2-iodo-benzyl)-methyl-amino]-ethanone 
• 103-67-3 benzyl-methyl-amine 
• 403-29-2 2-bromo-4'-fluoroacetophenone 
• 403-42-9 1-(4-fluorophenyl)ethanone 
• 456-04-2 2-Chloro-4'-fluoroacetophenone 

Downstream Products

• 133962-00-2 1-(4-fluorophenyl)-2-<(N-benzyl-N-methyl)amino>ethanol 
• 864961-02-4 [2-(4-fluorophenyl)-2-hydroxyethyl]methylcarbamic acid t-butyl ester 
• 864961-69-3 3-{[2-(4-Fluorophenyl)-2-hydroxy-ethyl]-methyl-sulfamoyl}-thiophene-2-carboxylic acid methyl ester 
• 864961-74-0 5-acetyl-2-amino-thiophene-3-sulfonic acid [2-(4-fluorophenyl)-2-hydroxy-ethyl]-methyl-amide 
• 864961-70-6 (3-{[2-(4-Fluorophenyl)-2-hydroxy-ethyl]-methyl-sulfamoyl}-thiophene-2-yl)-carbamic acid t-butyl ester 
• 864961-78-4 N-(5-Acetyl-3-{[2-(4-fluorophenyl)-2-hydroxy-ethyl]-methyl-sulfamoyl}-thiophene-2-yl)-propionic acid amide 
• 864961-72-8 (5-Bromo-3-{[2-(4-fluorophenyl)-2-hydroxy-ethyl]-methyl-sulfamoyl)-thiophene-2-yl)-carbamic acid t-butyl ester 
• 864961-76-2 (5-bromo-3-{[2-(4-fluorophenyl)-2-hydroxy-ethyl]-methyl-sulfamoyl}-thiophene-2-yl)-methyl-carbamic acid t-butyl ester 
• 864961-73-9 (5-Acetyl-3-{[2-(4-fluorophenyl)-2-hydroxy-ethyl]-methyl-sulfamoyl}-thiophene-2-yl)-carbamic acid t-butyl ester 
• 864961-79-5 N-(5-Acetyl-3-{[2-(4-fluorophenyl)-2-hydroxy-ethyl]-methyl-sulfamoyl}-thiophene-2-yl)-4-fluoro-benzamide 
• 864961-08-0 (2S)-[2-(4-fluorophenyl)-2-hydroxyethyl]methylcarbamic acid t-butyl ester 
• 864961-03-5 [2-azide-2-(4-fluorophenyl)ethyl]methylcarbamic acid t-butyl ester 
• 864961-71-7 C₁₄H₁₄FNO₅S₂ 
• 864961-07-9 (2S)-methoxyphenyl acetic acid (1R)-2-(t-butoxycarbonyl-methylamino)-1-(4-fluorophenyl)ethyl ester 

Relevant academic research and scientific papers

Heterocyclic compound having oxime group

The present invention provides a compound that has an excellent inhibitory activity on STAT6 activation and is effective against allergic diseases, and a medicinal composition thereof. According to the present invention, disclosed is the compound represented by the General Formula (I) [where R1 and R2 independently represent a C1-6 alkyl group and the like that may have a hydrogen atom or a substituent; R3 represents a C1-6 alkyl group and the like that may have a substituent; R4 and R5 independent represents a hydrogen atom or a C1-6 alkyl group and the like that may have a substituent; R6 represents a hydrogen atom and the like; W represents —SO2— and the like; and X represents a sulphur atom and the like.]or a salt thereof, or a hydrate thereof.

Synthesis, antiulcer and antidepressive activity of 4-(4-halophenyl)-2-phenyl-1,2,3,4-tetrahydroisoquinolines

4-(4-halophenyl)-2-methyl-1,2,3,4-tetrahydro-isoquinolines 2a-c have been synthesized by two methods and their biochemical and pharmacological properties have been studied. Biochemical investigations showed that all the compounds are strong inhibitors of

A convenient synthesis of 4-substituted 1,2,3,4-tetrahydroisoquinolin-4-ols by a novel intramolecular Barbier reaction and by an insertion reaction: Reaction scope and limitations

4-Substituted 1,2,3,4-tetrahydroisoquinolin-4-ols were prepared from N-(2-iodobenzyl)phenacylamines by an intramolecular Barbier reaction with butyllithium and by an insertion reaction with zerovalent nickel. The scope and limitations of these reactions were discussed.

A NEW INTRAMOLECULAR BARBIER REACTION OF N-(2-IODOBENZYL)PHENACYLAMINES: A CONVENIENT SYNTHESIS OF 1,2,3,4-TETRAHYDROISOQUINOLIN-4-OLS

4-Phenyl-1,2,3,4-tetrahydroisoquinolin-4-ols were prepared by an intramolecular Barbier reaction of N-(2-iodobenzyl)phenacylamines with butyllithium in good yields.