1313370-93-2Relevant academic research and scientific papers
A Selective C-C Bond Cleavage Strategy Promoted by Visible Light
Gallo, Rafael D. C.,Duarte, Marcelo,Da Silva, Amanda F.,Okada, Celso Y.,Deflon, Victor M.,Jurberg, Igor D.
supporting information, p. 8916 - 8920 (2021/11/20)
A new visible-light-promoted reaction between aryldiazoacetates and 1,3-diketones allows good yields and selectivities for C-C bond insertions, leading to the corresponding 1,4-dicarbonyl compounds. This transformation is straightforward and highly practical. It tolerates air and moisture and does not require the use of any metals. Mechanistic investigations support the involvement of a key cyclopropanol intermediate derived from an intramolecular rearrangement.
