872046-08-7Relevant academic research and scientific papers
Preparation method of 2-(2,6-difluorobenzyl)pyrrolidine
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Paragraph 0022; 0023; 0024, (2017/09/01)
The invention discloses a preparation method of 2-(2,6-difluorobenzyl)pyrrolidine. 2-(2,6-difluorobenzyl)acetic acid is used as a starting raw material, and a target product is obtained through esterification, coupling, ring opening, ring closing and redu
TRIAZOLOPYRIDINE ETHER DERIVATIVES AND THEIR USE IN NEUROLOGICAL AND PYSCHIATRIC DISORDERS
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Page/Page column 60, (2015/04/15)
The disclosure generally relates to compounds of formula I, including their salts, as well as compositions and methods of using the compounds. The compounds modulate the mGluR2 receptor and may be useful for the treatment of various disorders of the central nervous system.
NOVEL HETEROCYCLIC COMPOUNDS AS ERK INHIBITORS
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Page/Page column 209, (2012/01/14)
The present invention provides a compound of the Formula I:(Formular I should be inserted here) or a pharmaceutically acceptable salt, solvate or ester thereof, wherein R, R1, R2 and R3 are as defined herein. The compounds are ERK inhibitors. Also disclosed are pharmaceutical compositions comprising the above compounds and methods of treating cancer using the same.
NEW OXABISPIDINE COMPOUNDS FOR THE TREATMENT OF CARDIAC ARRHYTHMIAS
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Page/Page column 97, (2010/11/27)
There is provided compounds of formula I, [Chemical formula should be inserted here. Please see paper copy] wherein R1 to R4 , R41 to R46 and Z have meanings given in the description, which are useful in the prophylaxis and in the treatment of arrhythmias, in particular atrial and ventricular arrhythmias
NOVEL OXABISPIDINE COMPOUNDS AND THEIR USE IN THE TREATMENT OF CARDIAC ARRHYTHMIAS
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Page/Page column 95, (2008/06/13)
There is provided compounds of formula (I), wherein R1, R2, R3, R4, R 41 to R46, A, B and G have meanings given in the description, which are useful in the prophylaxis and in the treatment of arrhythmias, in particular atrial and ventricular arrhythmias.
