131341-69-0Relevant academic research and scientific papers
Conformational analysis of 5-lipoxygenase inhibitors: Role of the substituents in chiral recognition and on the active conformations of the (methoxyalkyl)thiazole and methoxytetrahydropyran series
Lambert-van der Brempt,Bruneau,Lamorlette
, p. 113 - 124 (2007/10/02)
The investigation of the SAR of 5-lipoxygenase (5-LO) inhibition of a series of racemic (methoxyalkyl)thiazoles, exemplified by compound 7 (ZM- 211965), has led to other active, racemic derivatives in which the thiazole moiety has been replaced by an este
HETEROCYCLIC ETHERS
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, (2008/06/13)
The invention concerns a heterocyclic ether of the formula I wherein Q is an optionally substituted 6-membered monocyclic or 10-membered bicyclic heterocyclic moiety containing one or two nitrogen atoms; A is (l-6C)alkylene, (3-6C)alkenylene, (3-6C)alkyny
CYCLIC ETHER DERIVATIVES
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, (2008/06/13)
The invention concerns a cyclic ether derivative of the formula I, wherein Ar 1 is optionally substituted phenyl or naphthyl; A 1 is (1-6C)alkylene, (3-6C)alkenylene, (3-6C)alkynylene or cyclo(3-6C)alkylene; Ar 2 is optionally substituted phenylene, or a
ALCOHOL AND ETHER DERIVATIVES
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, (2008/06/13)
The invention concerns a compound of the formula I, wherein Ar1 is optionally substituted phenyl or naphthyl; A1 is (1-6C)alkylene, (3-6C)alkenylene, (3-6C)alkynylene or cyclo(3-6C)alkylene; Ar2 is optionally substituted phenylene, or a 6 membered hetero
