1313429-31-0

Basic information

• Product Name: 3-[(1R,2R)-3-(dimethylamino)-1-ethyl-2-methylpropyl]phenol D-dibenzoyl tartaric acid salt
• Synonyms: 3-[(1R,2R)-3-(dimethylamino)-1-ethyl-2-methylpropyl]phenol D-dibenzoyl tartaric acid salt
• CAS NO: 1313429-31-0
• Molecular Weight: 579.647
• Mol File: 1313429-31-0.mol

Chemical Properties

• CAS DataBase Reference: 3-[(1R,2R)-3-(dimethylamino)-1-ethyl-2-methylpropyl]phenol D-dibenzoyl tartaric acid salt(CAS DataBase Reference)
• NIST Chemistry Reference: 3-[(1R,2R)-3-(dimethylamino)-1-ethyl-2-methylpropyl]phenol D-dibenzoyl tartaric acid salt(1313429-31-0)
• EPA Substance Registry System: 3-[(1R,2R)-3-(dimethylamino)-1-ethyl-2-methylpropyl]phenol D-dibenzoyl tartaric acid salt(1313429-31-0)

Safety Data

• Hazardous Substances Data: 1313429-31-0(Hazardous Substances Data)

Upstream product

• 175591-09-0 3-(3-dimethylamino-1-ethyl-2-methylpropyl)phenol hydrochloride 
• 17026-42-5 O,O'-dibenzoyl-D-tartaric acid 
• 175591-23-8 tapentadol 

Downstream Products

• 175591-09-0 tapentadol hydrochloride 

Relevant articles and documents

A NOVEL PROCESS FOR THE PREPARATION OF TAPENTADOL OR A PHARMACEUTICALLY ACCEPTABLE SALT THEREOF

Disclosed herein is a novel, commercially viable and industrially advantageous process for the preparation of 3-[(1R,2R))-3-(dimethylamino)-1-ethyl-2-methylpropyl]phenol (Tapentadol), or a pharmaceutically acceptable salt thereof, in high yield and purity. Also described are novel intermediates useful for preparing tapentadol or a pharmaceutically acceptable salt thereof.

SOLID STATE FORMS OF TAPENTADOL SALTS

Provided herein are novel solid state forms of tapentadol salts, process for their preparation, pharmaceutical compositions, and method of treating thereof. The tapentadol salts include an L-(?)-camphorsulfonate salt, a dibenzoyl-(L)-tartrate salt, a dibe