131346-50-4

Upstream product

• 3230-65-7 3,4-dihydroisoquinoline 
• 119813-92-2 5,8,13,13a-tetrahydro-8-oxo-6H-isoquino<2,1-g><1,6>naphthyridine 
• 60511-47-9 2-methylnicotinic acid diethylamide 
• 349-88-2 4-Fluorobenzenesulfonyl chloride 
• 119813-97-7 8aα,12aα,13aα-5,8,8a,9,10,11,12,12a,13,13a-decahydro-8-oxo-6H-isoquino<2,1-g><1,6>naphthyridine 

Relevant academic research and scientific papers

Structure-affinity relationships of 12-sulfonyl derivatives of 5,8,8a,9,10,11,12,12a,13,13a-decahydro-6H-isoquino[2,1-g][1,6] naphthyridines at α-adrenoceptors

Analogues of the potent α2-adrenoceptor antagonist (8aR,12aS,13aS)-5,8,8a,9,10,11,12,12a,13,13a-decahydro-3-methoxy-12- (methylsulfonyl)-6H-isoquino[2,1-g][1,6]naphthyridine (1b) were prepared and evaluated for α1- and α2-

Sulfonyl-decahydro-8H-isoquino[2,1-G][1,6]-naphthyridines and related compounds useful as α2 -blockers

Compounds of formulas (1) and (2): STR1 in which: X and Y are independently hydrogen, hydroxy, lower alkyl, lower alkoxy or halo, or X and Y taken together is methylenendioxy or ethylene-1,2-dioxy, and R is lower alkyl, optionally substituted phenyl, --(C